| Cat. No. |
Product Name |
Information |
| PC-21047 |
YHJ1039
FLT3 inhibitor
|
YHJ1039 is a broad-spectrum kinase inhibitor, possesses excellent potencies against FLT3 mutants (FLT3 D835Y, IC50=0.41 nM) as well as FAK (IC50=7 nM). |
| PC-20211 |
PCW-A1001
FLT3 D835Y inhibitor
|
PCW-A1001 is a potent, selective inhibitor of FLT-3 (D835Y) mutant with IC50 of 764 nM, weakly inhibits WT FLT-3 with IC50 of 2.54 uM. |
| PC-20025 |
HM43239
FLT3 inhibitor
|
HM43239 (Tuspetinib, HM-43239) is a highly potent, selective FLT3 kinase inhibitor with IC50 of 1.1 nM, 1.8 nM and 1.0 nM aginst FLT3 WT, FLT3 ITD and FLT3 D835Y kinases, respectively. |
| PC-47032 |
MBP-11901
Multikinase inhibitor
|
MBP-11901 is an orally active, multitarget tyrosine kinase inhibitor targeting FLT3, VEGFR2, PDGFRβ, and c-KIT, shows excellent inhibitory activity against HCC cell growth in vitro (HepG2, IC50=5.16 uM). |
| PC-38742 |
FLT3 inhibitor 7c
FLT3 inhibitor
|
FLT3 inhibitor 7c is a novel potent FLT3 inhibitor with IC50 of 207.2, 215.3 and 32.5 nM for FLT3 (WT), FLT3 (D835Y) and FLT3 (ITD), respectively. |
| PC-38618 |
FF-10101
FLT3 inhibitor
|
FF-10101 (FF10101) is a potent, selective, and irreversible FLT3 inhibitor with IC50 of 0.14 nM (FLT3 Wt), covalently binds to the C695 residue of FLT3. |
| PC-72759 |
CCT245718
Aurora A/FLT3 inhibitor
|
CCT245718 is a potent, dual Aurora A/FLT3 inhibitor with Kd of 39 nM (FLT3 D835Y) and 170 nM (FLT3 ITD), IC50 of 15 nM (Aurora A). |
| PC-72543 |
Marbotinib
FLT3 inhibitor
|
Marbotinib (FLT3i-3, Methanone 16) is a highly potent, specific, next-generation FLT3 inhibitor. |
| PC-72044 |
NCGC1481
IRAK1/4 inhibitor, FLT3 inhibitor
|
NCGC1481 (NCGC 1481) is a novel potent, type I kinase inhibitor against IRAK1/4 and FLT3, with IC50 of 22.6/0.8 nM and <0.5 nM respectively. |
| PC-35272 |
AAE871
FLT3 inhibitor
|
AAE871 (AAE-871) is a potent type I kinase inhibitor of FLT3 with IC50 of 34 nM, potently inhibits proliferation of FLT3-ITD- and D835Y-expressing cells (IC50<10 nM) through selective inhibition of FLT3 kinase activity. |
| PC-35271 |
ATH686
FLT3 inhibitor
|
ATH686 (ATH-686) is a potent and selective, second-generation inhibitor of mutant FLT3 protein kinase. |
| PC-35270 |
AUZ454
FLT3 inhibitor
|
AUZ454 (AUZ-454, K03861) is a potent and selective, second-generation inhibitor of mutant FLT3 protein kinase. |
