| Cat. No. |
Product Name |
Information |
| PC-20025 |
HM43239
FLT3 inhibitor
|
HM43239 (Tuspetinib, HM-43239) is a highly potent, selective FLT3 kinase inhibitor with IC50 of 1.1 nM, 1.8 nM and 1.0 nM aginst FLT3 WT, FLT3 ITD and FLT3 D835Y kinases, respectively. |
| PC-47032 |
MBP-11901
Multitarget TKI
|
MBP-11901 is an orally active, multitarget tyrosine kinase inhibitor targeting FLT3, VEGFR2, PDGFRβ, and c-KIT, shows excellent inhibitory activity against HCC cell growth in vitro (HepG2, IC50=5.16 uM). |
| PC-38742 |
FLT3 inhibitor 7c
FLT3 inhibitor
|
FLT3 inhibitor 7c is a novel potent FLT3 inhibitor with IC50 of 207.2, 215.3 and 32.5 nM for FLT3 (WT), FLT3 (D835Y) and FLT3 (ITD), respectively. |
| PC-38618 |
FF-10101
FLT3 inhibitor
|
FF-10101 (FF10101) is a potent, selective, and irreversible FLT3 inhibitor with IC50 of 0.14 nM (FLT3 Wt), covalent binds to the C695 residue of FLT3. |
| PC-50013 |
Quizartinib hydrochloride
|
Quizartinib (AC220) is a potent, selective, second-generation FLT3 inhibitor with Kd of 1.6 nM, inhibits Wt FLT3 and FLT3-ITD autophosphorylation in MV4-11cell with IC50 of 4.2 and 1.1 nM, respectively. |
| PC-61960 |
HEC-73543
|
HEC-73543 is a novel potent, selective, orally bioavailable FLT3 inhibitor for the treatment of refractory acute myeloid leukemia (AML). |
