| Cat. No. |
Product Name |
Information |
| PC-28554 |
ML356
FASN inhibitor
|
ML356 is a potent, selective inhibitor of the thioesterase (TE) domain of fatty acid synthase (FASN, FAS) (FASN-TE) with IC50 of 0.334 uM. |
| PC-28553 |
SBP-5917
FASN inhibitor
|
SBP-5917 is a potent, selective reversible, orally bioavailable inhibitor of thioesterase (TE) domain of fatty acid synthase (FASN) (FASN-TE) with IC50 of 120 nM in OMFH assays. |
| PC-27174 |
IQZ-1
FASN expression inhibitor
|
IQZ-1 is a small molecule inhibitor of fatty acid synthase (FASN) expression with IC50 of 0.6 uM in HuH-7 cells, inhibits FASN transcription at least via the proximal sterol regulatory elements of the FASN promoter. |
| PC-21673 |
FASstatin
FASN inhibitor
|
FASstatin (FASNi-8) is an orally bioavailable small-molecule inhibitor of fatty acid synthase (FASN), directly binds FASN with SPR KD of 16 uM, potentiates TRIM56-mediated FASN ubiquitination. |
| PC-21269 |
CMS121
FASN inhibitor
|
CMS121 (CMS-121) is a small molecule fatty acid synthase (FASN) inhibitor, reduces lipid peroxidation and neuroinflammation both in vitro and in vivo. |
| PC-20892 |
NJNU-0069-003
MHC-II inducer
|
NJNU-0069-003 is a specific small-molecule inducer of major histocompatibility complex class II (MHC-II), directly binds to the MAT domain of FASN with Kd of 7.98 uM. |
| PC-20891 |
NJNU-0069
MHC-II inducer
|
NJNU-0069 is a specific small-molecule inducer of major histocompatibility complex class II (MHC-II), directly binds to the MAT domain of FASN (Kd=32.1 uM). |
| PC-20378 |
Fasnall
FASN inhibitor
|
Fasnall is a potent, selective fatty acid synthase (FASN) inhibitor with IC50 of 3.71 uM for purified human FASN isolated from the BT474 cell line. |
| PC-20377 |
Fasnall benzenesulfonate
FASN inhibitor
|
Fasnall benzenesulfonate is a potent, selective fatty acid synthase (FASN) inhibitor with IC50 of 3.71 uM for purified human FASN isolated from the BT474 cell line. |
| PC-72780 |
TVB-3664
FASN inhibitor
|
TVB-3664 (TVB3664) is a potent, selective and highly bioavailable fatty acid synthase (FASN) inhibitor with IC50 of 18 nM and 12 nM for human and mouse cell palmitate synthesis, respectively. |
| PC-72348 |
FT113
FASN inhibitor
|
FT113 (FT-113) is a potent inhibitor of fatty acid synthase (FASN) with IC50 of 213 nM (hFASN). |
| PC-72346 |
TVB-2640
FASN inhibitor
|
TVB-2640 (Denifanstat, TVB2640) is a first-in-class, potent, selective, oral fatty acid synthase (FASN) inhibitor with IC50 of 52 nM. |
