| Cat. No. |
Product Name |
Information |
| PC-23173 |
NK-189
NS2B-NS3 inhibitor
|
NK-189 is a potent, specific flaviviral serine protease NS2B-NS3 inhibitor with submicromolar activities in viral replication assays (EC50=0.89 μM, DENV-2). |
| PC-23172 |
DENV NS2B-NS3 inhibitor 71
NS2B-NS3 inhibitor
|
DENV NS2B-NS3 inhibitor 71 is a potent, specific flaviviral serine protease NS2B-NS3 inhibitor with submicromolar activities in viral replication assays (EC50=0.24 μM, DENV-2). |
| PC-23171 |
NSC157058
NS2B-NS3 inhibitor
|
NSC157058 is a potent, allosteric inhibitor of ZIKV NS2B-NS3 protease with IC50 of 0.82 uM. |
| PC-23170 |
SYC-1307
NS2B-NS3 inhibitor
|
SYC-1307 is a potent, allosteric inhibitor of flavivirus NS2B-NS3 protease with IC50 of 0.2, 0.59, 0.59 and 0.78 uM for ZIKV, DENV2, DENV3 and WNV NS2B-NS3 respectively, shows submicromolar anti-orthoflaviviral efficacy in cells (EC50=0.3-0.6 uM). |
| PC-22506 |
CVM-2-12-2
DENV E protein inhibitor
|
CVM-2-12-2 is a selective and potent inhibitor of the envelope (E) protein of dengue virus (DENV), demonstrates potent antiviral activity. |
| PC-22064 |
ARDP0006
DENV inhibitor
|
ARDP0006 is a potent inhibitor of dengue virus (DENV) NS2B-NS3 protease with EC50 of 4.2 uM. |
| PC-22063 |
DV-B-120
DENV inhibitor
|
DV-B-120 is a potent inhibitor of dengue virus (DENV) NS2B-NS3 protease, demonstrates superior inhibition of NS2B-NS3 protease activity and lower toxicity compared to ARDP0006. |
| PC-21749 |
PS3061
Sec61 modulator
|
PS3061 (PS 3061) is a substrate-selective co-translational translocation inhibitor, modulates SEC61 translocon and inhibits both DENV and ZIKV virion production and replication. |
| PC-21748 |
Cotransin CT9
Sec61 modulator
|
Cotransin CT9 (CT-09) is a substrate-selective co-translational translocation inhibitor, binds the Sec61 translocon to inhibit cotranslational translocation of a subset of secreted and type I transmembrane proteins. |
| PC-21747 |
Cotransin CT8
Sec61 modulator
|
Cotransin CT8 (CT-08) is a substrate-selective co-translational translocation inhibitor, binds the Sec61 translocon to inhibit cotranslational translocation of a subset of secreted and type I transmembrane proteins. |
| PC-21361 |
Compound 11064
DENV inhibitor
|
Compound 11064 is a baicalein-derived compound with potent activity against DENV and ZIKV, displays pan-serotype DENV and ZIKV antiviral activity in vitro in the low micromolar range. |
