| Cat. No. |
Product Name |
Information |
| PC-22063 |
DV-B-120
DENV inhibitor
|
DV-B-120 is a potent inhibitor of dengue virus (DENV) NS2B-NS3 protease, demonstrates superior inhibition of NS2B-NS3 protease activity and lower toxicity compared to ARDP0006. |
| PC-21967 |
Arbemnifosbuvir
DENV inhibitor
|
Arbemnifosbuvir (AT-752) a double prodrug of a guanosine nucleotide analog with activity against dengue virus (DENV), potently inhibits DENV1-4 with EC50 of 0.5 uM in Huh-7 cells, inhibits NS5 active site of all four DENV1-4 NS5 RdRps. |
| PC-21749 |
PS3061
Sec61 modulator
|
PS3061 (PS 3061) is a substrate-selective co-translational translocation inhibitor, modulates SEC61 translocon and inhibits both DENV and ZIKV virion production and replication. |
| PC-21748 |
Cotransin CT9
Sec61 modulator
|
Cotransin CT9 (CT-09) is a substrate-selective co-translational translocation inhibitor, binds the Sec61 translocon to inhibit cotranslational translocation of a subset of secreted and type I transmembrane proteins. |
| PC-21747 |
Cotransin CT8
Sec61 modulator
|
Cotransin CT8 (CT-08) is a substrate-selective co-translational translocation inhibitor, binds the Sec61 translocon to inhibit cotranslational translocation of a subset of secreted and type I transmembrane proteins. |
| PC-21361 |
Compound 11064
DENV inhibitor
|
Compound 11064 is a baicalein-derived compound with potent activity against DENV and ZIKV, displays pan-serotype DENV and ZIKV antiviral activity in vitro in the low micromolar range. |
