| Cat. No. |
Product Name |
Information |
| PC-35009 |
JNJ-1A
DENV NS4B inhibitor
|
JNJ-1A is a novel Dengue virus (DENV) NS4B inhibitor that inhibits DENV-2 sub-genomic replicon at 0.7 μM, in the absence of cytotoxicity. |
| PC-35008 |
ST-148
DENV inhibitor
|
ST-148 is a potent, broad-spetrum inhibitor of dengue virus (DENV) replication, inhibits DENV-2 wth EC50 of 16 nM in viral titer reduction assays, interacts with the DENV capsid protein. |
| PC-35007 |
VGTI-A3-03
DENV inhibitor
|
VGTI-A3-03 is a potent, highly virus-specific inhibitor of DENV replication with greatest activity against DENV serotype 2 (IC50=25 nM), directly binds DENV capsid protein. |
| PC-63346 |
SFV785
NTRK1/MAPKAPK5 inhibitor
|
SFV785 (SRPIN-785) is a derivative of SRPIN340 that selectively inhibits NTRK1 and MAPKAPK5 kinase, shows anti-viral activity on HCV, DENV and yellow fever viruses. |
| PC-60960 |
MK-0608
HCV inhibitor
|
MK-0608 is a nucleoside analogue that shows potent inhibition for replication of several mosquito-borne flaviviruses including DENV and ZIKV. |
| PC-60313 |
GS-5734
SARS-CoV-2 inhibitor
|
GS-5734 (Remdesivir) is a monophosphoramidate prodrug of adenosine analogue that exhibits antiviral activity against multiple variants of EBOV (EC50=70-140 nM) and other filoviruses (EC50=0.019-1.48 uM) in cell-based assays. |
| PC-23175 |
Methylene Blue
DENV NS2B-NS3 inhibitor
|
Methylene blue (Basic Blue 9) is a guanylyl cyclase (sGC), monoamine oxidase A (MAO-A) and NO synthase (NOS) inhibitor, also is a Tau aggregation inhibitor, inhibits DENV NS2B-NS3 inhibitor (IC50=9 µM) and DENV infection in cells in the submicromolar range (EC50=0.36 µM). |
| PC-23174 |
Temoporfin
NS2B-NS3 inhibitor
|
Temoporfin (m-THPC) is a reduced porphyrin and potent second-generation photosensitizer, also is a potent flavivirus NS2B-NS3 interaction inhibitor with broad-spectrum antiviral activity. |
| PC-23173 |
NK-189
NS2B-NS3 inhibitor
|
NK-189 is a potent, specific flaviviral serine protease NS2B-NS3 inhibitor with submicromolar activities in viral replication assays (EC50=0.89 μM, DENV-2). |
| PC-23172 |
DENV NS2B-NS3 inhibitor 71
NS2B-NS3 inhibitor
|
DENV NS2B-NS3 inhibitor 71 is a potent, specific flaviviral serine protease NS2B-NS3 inhibitor with submicromolar activities in viral replication assays (EC50=0.24 μM, DENV-2). |
| PC-23171 |
NSC157058
NS2B-NS3 inhibitor
|
NSC157058 is a potent, allosteric inhibitor of ZIKV NS2B-NS3 protease with IC50 of 0.82 uM. |
| PC-23170 |
SYC-1307
NS2B-NS3 inhibitor
|
SYC-1307 is a potent, allosteric inhibitor of flavivirus NS2B-NS3 protease with IC50 of 0.2, 0.59, 0.59 and 0.78 uM for ZIKV, DENV2, DENV3 and WNV NS2B-NS3 respectively, shows submicromolar anti-orthoflaviviral efficacy in cells (EC50=0.3-0.6 uM). |
