| Cat. No. |
Product Name |
Information |
| PC-45502 |
Galidesivir hydrochloride
Viral RdRp inhibitor
|
Galidesivir hydrochloride (BCX4430) is a viral RNA-dependent RNA polymerase (RdRp) inhibitor that acts as a non-obligate RNA chain terminator, inhibits MERS-CoV, SARS-CoV and SARS-CoV-2. |
| PC-26719 |
JNJ-1953
Orthoflavivirus NS2A inhibitor
|
JNJ-1953 is an orthoflavivirus inhibitor targeting multifunctional NS2A protein, shows nM potency against DENV-2 clinical isolates DENV-2/EDEN3295 and DENV-2/38865Y10, affects viral RNA synthesis and packaging. |
| PC-26381 |
Berbamine
EBOV inhibitor, Gal3 inhibitor
|
Berbamine is a natural bisbenzylisoquinoline alkaloidshows broad exhibits anti-tumor and anti-viral activies, inhibits Ebola virus (EBOV) and prevents SARS-CoV-2 entry. |
| PC-26380 |
Berbamine hydrochloride
EBOV inhibitor, Gal3 inhibitor
|
Berbamine hydrochloride is a natural bisbenzylisoquinoline alkaloidshows broad exhibits anti-tumor and anti-viral activies, inhibits Ebola virus (EBOV) and prevents SARS-CoV-2 entry. |
| PC-25591 |
NSC135618
Flavivirus NS2B-NS3 inhibitor
|
NSC135618 is a potent, allosteric inhibitor of the flavivirus NS2B-NS3 protease, inhibits the protease of Dengue virus 2 (DENV2) in vitro with IC50 of 1.8 uM, shows broad spectrum flavivirus protease, inhibits DENV2, Zika virus (ZIKV), West Nile virus (WNV), and Yellow fever virus (YFV) on A549 cells in vivo with EC50 in low micromolar range. |
| PC-24464 |
HeE1-2Tyr
Flavivirus RdRp inhibitor
|
HeE1-2Tyr is a potent, nonnucleoside inhibitor of flavivirus RNA dependent RNA polymerase (RdRp) with IC50 of 1.5 uM and 3.4 uM for DENV3 and WNV RdRps, respectively, also is a SARS-CoV-2 RdRp with IC50 of 27.6 uM. |
| PC-23620 |
Compound 3.47
EBOV inhibitor
|
Compound 3.47 is a small molecule antifilovirus compound, inhibits EboV infection by interfering with binding of cleaved virus glycoprotein (GP) to endosomal membrane protein Niemann-Pick C1 (NPC1). |
| PC-23619 |
EBOV inhibitor Compound 7
EBOV inhibitor
|
EBOV inhibitor Compound 7 is a a small-molecule entry inhibitor of filoviruses, inhibits infectious EBOV and Marburg virus (MARV) in cell-based assays with IC50 of 10 μM and 12 μM, respectively. |
| PC-23617 |
CBS1129
Filovirus inhibitor
|
CBS1129 is a small molecule inhibitor of filovirus entry, shows potent inhibitory activity against entry of both Ebola and Marburg viruses in human cancer cell lines (EC50=2.4 uM, pseudovirus (HIV/EBOV) assay). |
| PC-23615 |
VUN65671
EBOV/MARV inhibitor
|
VUN65671 is a potent small molecule inhibitor of Ebola (EBOV) and Marburg (MARV) virus entry with EC50 of 0.31 uM and 0.82 uM. |
| PC-23175 |
Methylene Blue
DENV NS2B-NS3 inhibitor
|
Methylene blue (Basic Blue 9) is a guanylyl cyclase (sGC), monoamine oxidase A (MAO-A) and NO synthase (NOS) inhibitor, also is a Tau aggregation inhibitor, inhibits DENV NS2B-NS3 inhibitor (IC50=9 µM) and DENV infection in cells in the submicromolar range (EC50=0.36 µM). |
| PC-23174 |
Temoporfin
NS2B-NS3 inhibitor
|
Temoporfin (m-THPC) is a reduced porphyrin and potent second-generation photosensitizer, also is a potent flavivirus NS2B-NS3 interaction inhibitor with broad-spectrum antiviral activity. |
