Cat. No. |
Product Name |
Information |
PC-23167 |
EYU688 (NITD-688)
DENV NS4B inhibitor
|
EYU688 (NITD-688) is a potent, specific pan-serotype inhibitor of dengue virus (DENV) NS4B protein, shows EC50 of 8-38 nM against all four DENV serotypes. |
PC-22506 |
CVM-2-12-2
DENV E protein inhibitor
|
CVM-2-12-2 is a selective and potent inhibitor of the envelope (E) protein of dengue virus (DENV), demonstrates potent antiviral activity. |
PC-22064 |
ARDP0006
DENV inhibitor
|
ARDP0006 is a potent inhibitor of dengue virus (DENV) NS2B-NS3 protease with EC50 of 4.2 uM. |
PC-22063 |
DV-B-120
DENV inhibitor
|
DV-B-120 is a potent inhibitor of dengue virus (DENV) NS2B-NS3 protease, demonstrates superior inhibition of NS2B-NS3 protease activity and lower toxicity compared to ARDP0006. |
PC-21967 |
Arbemnifosbuvir
DENV inhibitor
|
Arbemnifosbuvir (AT-752) a double prodrug of a guanosine nucleotide analog with activity against dengue virus (DENV), potently inhibits DENV1-4 with EC50 of 0.5 uM in Huh-7 cells, inhibits NS5 active site of all four DENV1-4 NS5 RdRps. |
PC-21749 |
PS3061
Sec61 modulator
|
PS3061 (PS 3061) is a substrate-selective co-translational translocation inhibitor, modulates SEC61 translocon and inhibits both DENV and ZIKV virion production and replication. |
PC-21748 |
Cotransin CT9
Sec61 modulator
|
Cotransin CT9 (CT-09) is a substrate-selective co-translational translocation inhibitor, binds the Sec61 translocon to inhibit cotranslational translocation of a subset of secreted and type I transmembrane proteins. |
PC-21747 |
Cotransin CT8
Sec61 modulator
|
Cotransin CT8 (CT-08) is a substrate-selective co-translational translocation inhibitor, binds the Sec61 translocon to inhibit cotranslational translocation of a subset of secreted and type I transmembrane proteins. |
PC-21361 |
Compound 11064
DENV inhibitor
|
Compound 11064 is a baicalein-derived compound with potent activity against DENV and ZIKV, displays pan-serotype DENV and ZIKV antiviral activity in vitro in the low micromolar range. |
PC-62053 |
FGI-106
|
FGI-106 is a broad-spectrum inhibitor of multiple blood-borne viruses (HCV, HBV, HIV) as well as emerging biothreats (Ebola, VEE, Cowpox, PRRSV infection) with EC50 of 0.2-10 uM. |
PC-62052 |
FGI-104
|
FGI-104 is a small-molecule inhibitor of filovirus that exhibits potent antiviral activity against of EBOV (EC90=330 nM, ZEBOV) and MARV (EC50=2.5 uM, MARV-Ci67). |
PC-62051 |
FGI-103
|
FGI-103 is a small-molecule inhibitor of filovirus that exhibits potent antiviral activity against of EBOV (EC90=330 nM, ZEBOV) and MARV (EC50=2.5 uM, MARV-Ci67). |