Cat. No. |
Product Name |
Information |
PC-23619 |
EBOV inhibitor Compound 7
EBOV inhibitor
|
EBOV inhibitor Compound 7 is a a small-molecule entry inhibitor of filoviruses, inhibits infectious EBOV and Marburg virus (MARV) in cell-based assays with IC50 of 10 μM and 12 μM, respectively. |
PC-23617 |
CBS1129
Filovirus inhibitor
|
CBS1129 is a small molecule inhibitor of filovirus entry, shows potent inhibitory activity against entry of both Ebola and Marburg viruses in human cancer cell lines (EC50=2.4 uM, pseudovirus (HIV/EBOV) assay). |
PC-23615 |
VUN65671
EBOV/MARV inhibitor
|
VUN65671 is a potent small molecule inhibitor of Ebola (EBOV) and Marburg (MARV) virus entry with EC50 of 0.31 uM and 0.82 uM. |
PC-23175 |
Methylene Blue
DENV NS2B-NS3 inhibitor
|
Methylene blue (Basic Blue 9) is a guanylyl cyclase (sGC), monoamine oxidase A (MAO-A) and NO synthase (NOS) inhibitor, also is a Tau aggregation inhibitor, inhibits DENV NS2B-NS3 inhibitor (IC50=9 µM) and DENV infection in cells in the submicromolar range (EC50=0.36 µM). |
PC-23174 |
Temoporfin
NS2B-NS3 inhibitor
|
Temoporfin (m-THPC) is a reduced porphyrin and potent second-generation photosensitizer, also is a potent flavivirus NS2B-NS3 interaction inhibitor with broad-spectrum antiviral activity. |
PC-23173 |
NK-189
NS2B-NS3 inhibitor
|
NK-189 is a potent, specific flaviviral serine protease NS2B-NS3 inhibitor with submicromolar activities in viral replication assays (EC50=0.89 μM, DENV-2). |
PC-23172 |
DENV NS2B-NS3 inhibitor 71
NS2B-NS3 inhibitor
|
DENV NS2B-NS3 inhibitor 71 is a potent, specific flaviviral serine protease NS2B-NS3 inhibitor with submicromolar activities in viral replication assays (EC50=0.24 μM, DENV-2). |
PC-23171 |
NSC157058
NS2B-NS3 inhibitor
|
NSC157058 is a potent, allosteric inhibitor of ZIKV NS2B-NS3 protease with IC50 of 0.82 uM. |
PC-23170 |
SYC-1307
NS2B-NS3 inhibitor
|
SYC-1307 is a potent, allosteric inhibitor of flavivirus NS2B-NS3 protease with IC50 of 0.2, 0.59, 0.59 and 0.78 uM for ZIKV, DENV2, DENV3 and WNV NS2B-NS3 respectively, shows submicromolar anti-orthoflaviviral efficacy in cells (EC50=0.3-0.6 uM). |
PC-23167 |
EYU688 (NITD-688)
DENV NS4B inhibitor
|
EYU688 (NITD-688) is a potent, specific pan-serotype inhibitor of dengue virus (DENV) NS4B protein, shows EC50 of 8-38 nM against all four DENV serotypes. |
PC-22506 |
CVM-2-12-2
DENV E protein inhibitor
|
CVM-2-12-2 is a selective and potent inhibitor of the envelope (E) protein of dengue virus (DENV), demonstrates potent antiviral activity. |
PC-22064 |
ARDP0006
DENV inhibitor
|
ARDP0006 is a potent inhibitor of dengue virus (DENV) NS2B-NS3 protease with EC50 of 4.2 uM. |