| Cat. No. |
Product Name |
Information |
| PC-60960 |
MK-0608
HCV inhibitor
|
MK-0608 is a nucleoside analogue that shows potent inhibition for replication of several mosquito-borne flaviviruses including DENV and ZIKV. |
| PC-60313 |
Remdesivir
SARS-CoV-2 inhibitor
|
Remdesivir (GS-5734) is a monophosphoramidate prodrug of adenosine analogue that exhibits antiviral activity against multiple variants of EBOV (EC50=70-140 nM) and other filoviruses (EC50=0.019-1.48 uM) in cell-based assays. |
| PC-45503 |
Galidesivir
Viral RdRp inhibitor
|
Galidesivir (BCX4430) is a viral RNA-dependent RNA polymerase (RdRp) inhibitor that acts as a non-obligate RNA chain terminator, inhibits MERS-CoV, SARS-CoV and SARS-CoV-2. |
| PC-45502 |
Galidesivir hydrochloride
Viral RdRp inhibitor
|
Galidesivir hydrochloride (BCX4430) is a viral RNA-dependent RNA polymerase (RdRp) inhibitor that acts as a non-obligate RNA chain terminator, inhibits MERS-CoV, SARS-CoV and SARS-CoV-2. |
| PC-26719 |
JNJ-1953
Orthoflavivirus NS2A inhibitor
|
JNJ-1953 is an orthoflavivirus inhibitor targeting multifunctional NS2A protein, shows nM potency against DENV-2 clinical isolates DENV-2/EDEN3295 and DENV-2/38865Y10, affects viral RNA synthesis and packaging. |
| PC-26381 |
Berbamine
EBOV inhibitor, Gal3 inhibitor
|
Berbamine is a natural bisbenzylisoquinoline alkaloidshows broad exhibits anti-tumor and anti-viral activies, inhibits Ebola virus (EBOV) and prevents SARS-CoV-2 entry. |
| PC-26380 |
Berbamine hydrochloride
EBOV inhibitor, Gal3 inhibitor
|
Berbamine hydrochloride is a natural bisbenzylisoquinoline alkaloidshows broad exhibits anti-tumor and anti-viral activies, inhibits Ebola virus (EBOV) and prevents SARS-CoV-2 entry. |
| PC-24464 |
HeE1-2Tyr
Flavivirus RdRp inhibitor
|
HeE1-2Tyr is a potent, nonnucleoside inhibitor of flavivirus RNA dependent RNA polymerase (RdRp) with IC50 of 1.5 uM and 3.4 uM for DENV3 and WNV RdRps, respectively, also is a SARS-CoV-2 RdRp with IC50 of 27.6 uM. |
| PC-23620 |
Compound 3.47
EBOV inhibitor
|
Compound 3.47 is a small molecule antifilovirus compound, inhibits EboV infection by interfering with binding of cleaved virus glycoprotein (GP) to endosomal membrane protein Niemann-Pick C1 (NPC1). |
| PC-23619 |
EBOV inhibitor Compound 7
EBOV inhibitor
|
EBOV inhibitor Compound 7 is a a small-molecule entry inhibitor of filoviruses, inhibits infectious EBOV and Marburg virus (MARV) in cell-based assays with IC50 of 10 μM and 12 μM, respectively. |
| PC-23617 |
CBS1129
Filovirus inhibitor
|
CBS1129 is a small molecule inhibitor of filovirus entry, shows potent inhibitory activity against entry of both Ebola and Marburg viruses in human cancer cell lines (EC50=2.4 uM, pseudovirus (HIV/EBOV) assay). |
| PC-23615 |
VUN65671
EBOV/MARV inhibitor
|
VUN65671 is a potent small molecule inhibitor of Ebola (EBOV) and Marburg (MARV) virus entry with EC50 of 0.31 uM and 0.82 uM. |
