| Cat. No. |
Product Name |
Information |
| PC-20394 |
BVT173187
FPR1 inhibitor
|
BVT173187 is a potent, selective, non-peptide inhibitor of formyl peptide receptor 1 (FPR1), inhibits fMLF and WKYMVM induced oxidase activity. |
| PC-20393 |
Quin-C1
FPR2 agonist
|
Quin C1 is a potent and selective FPR2 agonist with EC50 of 15 nM, induces Ca2+ mobilization in FPR2 but not FPR1-transfected mast cells. |
| PC-20392 |
HCH6-1
FPR1 inhibitor
|
HCH6-1 is a selective, competitive formyl peptide receptor 1 (FPR1) antagonist, superoxide anion generation in fMLF (FPR1 agonist)-activated neutrophils with IC50 of 0.32 uM in cell-impermeable cytochrome c reduction assay. |
| PC-20391 |
WRW4
FPR2 inhibitor
|
WRW4 (Trp-Arg-Trp-Trp-Trp-Trp) is a selective antagonist of formyl peptide receptor 2 (FPR2, FPRL1) signaling, inhibits WKYMVm binding to FPR2 with IC50 of 0.23 uM. |
| PC-49033 |
BMS-986235
FPR2 agonist
|
BMS-986235 (LAR-1219) is a potent, selective, and orally bioavailable agonist of formyl peptide receptor 2 (FPR2) with EC50 of 0.4 nM (hFPR2), >7,000-fold selectivity over FPR1. |
| PC-72355 |
FPR2 inhibitor (S)-11l
FPR2 agonist
|
FPR2 inhibitor (S)-11l is a potent, selective, brain penetrant FPR2 agonist with IC50 of 0.13 uM (hFPR2). |
| PC-72086 |
FPR agonist Compound 43
FPR agonist
|
FPR agonist Compound 43 is a potent agonist of human formyl-peptide-like 1 receptor (hFPRL1) with EC50 of 44 nM (hFPRL1-mediated Ca2+ mobilization). |
| PC-72085 |
FPR agonist Compound 17b
FPR agonist
|
FPR agonist Compound 17b is a small-molecule FPR1/FPR2 agonist withEC50 of 3.2 uM (hFPR1 Ca2+ mobilization), lack of functional responses at FPR3. |
| PC-72084 |
WKYMVm hexapeptide
pan-FPR agonist
|
WKYMVm hexapeptide is a potent, selective, pan-agonist for the formyl peptide receptors FPR1, FPR2 (EC50 = 75 pM) and FPR3 (EC50 = 3 nM). |
| PC-72083 |
FPR1 agonist fMLF
FPR1 agonist
|
FPR1 agonist fMLF (NSC 350593) is a potent, selective formylpeptide receptor-1 (FPR1) agonist with EC50 of 80 nM in calcium flux, Ki of 38 nM. |
| PC-72082 |
ICT12035
FPR1 antagonist
|
ICT12035 (AZ2158) is a potent, selective formylpeptide receptor-1 (FPR1) antagonist with IC50 of 30 nM in calcium mobilisation assays (100 nM fMLF). |
| PC-62594 |
ACT-389949
FPR2 agonist
|
ACT-389949 (ACT389949) is a novel potent and selective formyl peptide receptor type 2 (FPR2)/Lipoxin A4 receptor (ALX) agonist with EC50 of 3 nM for FPR2/ALX internalization into monocytes. |
