| Cat. No. |
Product Name |
Information |
| PC-60526 |
Opiranserin
GlyT2 inhibitor
|
Opiranserin (VVZ-149, VVZ-000149) is a potent, selective, mixed glycine GlyT2 transporter blocker (IC50= 0.86 uM), purine P2X3 receptor antagonist (IC50=0.87 uM) and serotonin 5-HT2A receptor antagonist (IC50=1.3 uM). |
| PC-60446 |
ALX-1393
GlyT2 inhibitor
|
ALX-1393 (ALX 1393, ALX1393) is a potent, specific GlyT2 inhibitor with Ki of <1 uM. |
| PC-60445 |
Org 25543
GlyT2 inhibitor
|
Org 25543 is a potent, highly selective glycine transporter 1 (GlyT2) inhibitor with IC50 of 16 nM with negligible affinity for GlyT1. |
| PC-60444 |
Org 25935
GlyT1 inhibitor
|
Org 25935 (SCH 900435) is a potent, selective glycine transporter 1 (GlyT1) inhibitor with IC50 of 100 nM. |
| PC-42145 |
LY2365109 hydrochloride
GlyT1 inhibitor
|
LY2365109 hydrochloride is a potent and selective GlyT1 inhibitor with IC50 of 15.8 nM, displays no activity for GlyT2 (IC50>30 uM). |
| PC-42706 |
Bitopertin
GlyT1 inhibitor, Nrf2 activator
|
Bitopertin (RG1678, RO4917838) is a potent and selective glycine uptake GlyT1 inhibitor with EC50 of 30 nM, also is an Nrf2 activator. |
| PC-42707 |
Bitopertin R enantiomer
|
A potent and selective GlyT1 inhibitor with EC50 of 54 nM. |
