| Cat. No. |
Product Name |
Information |
| PC-45230 |
Mevastatin
HMGCR inhibitor
|
Mevastatin (ML236B) is a hypolipidemic agentt that inhibits HMGCR (HMG-CoA reductase). |
| PC-21969 |
Bemfivastatin
HMGCR inhibitor
|
Bemfivastatin (PPD-10558) is an orally active, lipid-lowering 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor for treatment of hypercholesterolemia. |
| PC-49778 |
Apomine
HMGCR degrader
|
Apomine (SR-45023A) is an oral biphosphonate antineoplastic compound inhibiting HMG-CoA reductase, induces HMG-CoA reductase degradation with EC50 of 0.88 uM. |
| PC-49777 |
SRK2128
HMGCR degrader
|
SRK2128 (SRK 2128) is a highly potent HMG-CoA reductase degrader with EC50 of 84 nM, potently induce degradation of HMG-CoA reductase. |
| PC-45539 |
BRD-7116
|
A selective inhibitor of leukemia stem cells (LSCs) via inhibition of HMG-CoA reductase. |
| PC-45300 |
Simvastatin
|
A potent, competitive inhibitor of HMG-CoA reductase (HMGCR) with Kd of 0.1-0.2 nM. |
| PC-45305 |
Rosuvastatin
|
A potent, competitive inhibitor of HMG-CoA reductase (HMGCR) with IC50 of 11 nM. |
| PC-45304 |
Rosuvastatin calcium
|
A potent, competitive inhibitor of HMG-CoA reductase (HMGCR) with IC50 of 11 nM. |
| PC-46757 |
Atorvastatin
|
A competitive inhibitor of HMG-CoA reductase that acts as a lipid-lowering agent for prevention of events associated with cardiovascular disease.. |
| PC-45201 |
Atorvastatin hemicalcium
|
A competitive inhibitor of HMG-CoA reductase (HMGCR) that acts as a lipid-lowering agent for prevention of events associated with cardiovascular disease.. |
