| Cat. No. |
Product Name |
Information |
| PC-49778 |
Apomine
HMGCR inhibitor
|
Apomine (SR-45023A) is an oral biphosphonate antineoplastic compound inhibiting HMG-CoA reductase, induces HMG-CoA reductase degradation with EC50 of 0.88 uM. |
| PC-49777 |
SRK2128
HMGCR degrader
|
SRK2128 (SRK 2128) is a highly potent HMG-CoA reductase degrader with EC50 of 84 nM, potently induce degradation of HMG-CoA reductase. |
| PC-45539 |
BRD7116
HMGCR inhibitor
|
BRD7116 selective inhibitor of leukemia stem cells (LSCs) via inhibition of HMG-CoA reductase (HMGCR). |
| PC-45300 |
Simvastatin
HMGCR inhibitor
|
Simvastatin (MK-733) is a potent, competitive inhibitor of HMG-CoA reductase (HMGCR) with Kd of 0.1-0.2 nM. |
| PC-45305 |
Rosuvastatin
HMGCR inhibitor
|
Rosuvastatin (ZD-4522) is a potent, competitive inhibitor of HMG-CoA reductase (HMGCR) with IC50 of 11 nM. |
| PC-45304 |
Rosuvastatin calcium
HMGCR inhibitor
|
Rosuvastatin (ZD-4522) calcium is a potent, competitive inhibitor of HMG-CoA reductase (HMGCR) with IC50 of 11 nM. |
| PC-45230 |
Mevastatin
HMGCR inhibitor
|
Mevastatin (ML236B) is a hypolipidemic agentt that inhibits HMGCR (HMG-CoA reductase). |
| PC-46757 |
Atorvastatin
HMGCR inhibitor
|
Atorvastatin is a competitive inhibitor of HMG-CoA reductase (HMGCR) that acts as a lipid-lowering agent for prevention of events associated with cardiovascular disease. |
| PC-45201 |
Atorvastatin hemicalcium
HMGCR inhibitor
|
Atorvastatin hemicalcium is a competitive inhibitor of HMG-CoA reductase (HMGCR) that acts as a lipid-lowering agent for prevention of events associated with cardiovascular disease. |
| PC-23009 |
Pravastatin sodium
HMGCR inhibitor
|
Pravastatin (CS-514) sodium is a selective HMG-CoA reductase (HMGCR) inhibitor with IC50 of 5.6 uM against sterol synthesis. |
| PC-23008 |
Lovastatin
HMGCR inhibitor
|
Lovastatin is a cell-permeable HMGCR (HMG-CoA reductase) inhibitor, shows cholesterol lowering effect. |
| PC-21969 |
Bemfivastatin
HMGCR inhibitor
|
Bemfivastatin (PPD-10558) is an orally active, lipid-lowering 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor for treatment of hypercholesterolemia. |
