Cat. No. |
Product Name |
Information |
PC-20021 |
Apoxidole-1
IDO1 inhibitor
|
Apoxidole-1 is a potent, selective type IV inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), Apoxidole-1 reduces cellular kynurenine (Kyn) levels with IC50 of 46.7 in HeLa cells, but does not inhibit IDO1 expression. |
PC-49663 |
NLG802
IDO inhibitor
|
NLG-802 (NLG802) is a next-generation indoleamine-2,3-dioxygenase (IDO) pathway inhibitor and a prodrug of indoximod, shows increased oral bioavailability and maximum exposure. |
PC-49659 |
LY3410738
mutant IDH1 inhibitor
|
LY3410738 (LY 3410738) is a potent, selective, and covalent inhibitor of mutant IDH1 (IDH1-R132), LY3410738 is more effective than Ivosidenib (Cat#PC-45550) and potentiates antileukemic activity of AML. |
PC-72378 |
BMS-986242
IDO1 inhibitor
|
BMS-986242 (BMS986242) is a potent, selective IDO1 inhibitor with IC50 of 2 nM in cellular IDO1 inhibition assays and IC50 of 25 nM in human whole blood (HWB) IDO1 inhibition assays. |
PC-38081 |
PCC0208009
IDO inhibitor
|
PCC0208009 is a novel indoleamine 2,3-dioxygenase (IDO) inhibitor with IC50 of 4.52 nM at the cellular level. |
PC-60068 |
BMS-986205
|
BMS-986205 (Linrodostat, F-001287, ONO-7701) is a novel potent, selective and orally available IDO1 inhibitor with IC50 of 1.1 nM in cell-based assays. |
PC-45552 |
Navoximod
|
Navoximod (GDC-0919, NLG-919) is a potent, selective inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1) with biochemical IC50 of 28 nM, and of Ki of 5.8 nM. |
PC-45061 |
Indoximod
|
Indoximod (NLG-8189, 1-Methyl-D-tryptophan, D-1MT) is a potent Indoleamine 2,3-dioxygenase (IDO) inhibitor with IC50 of 7 uM. |
PC-42320 |
PF-06840003
|
PF-06840003 is a novel potent, selective, orally active, and CNS penetrant IDO-1 inhibitor with IC50 of 0.41 uM for hIDO-1. |
PC-22837 |
LW106
IDO1 inhibitor
|
LW106 is a selective indoleamine-2,3-dioxygenase 1 (IDO1) inhibitor with IC50 of 1.57 uM in IFN‐γ‐stimulated HeLa cells. |
PC-22836 |
Epacadostat
IDO1 inhibitor
|
Epacadostat (INCB24360, INCB024360) is a hihgly potent and selective, oral bioavailable indoleamine-2,3-dioxygenase 1 (IDO1) inhibitor with IC50 of 73 nM. |
PC-22274 |
Coptisine chloride
METTL3 inhibitor, IDO inhibitor
|
Coptisine chloride is an alkaloid from Chinese goldthread, and is an efficient uncompetitive indoleamine 2,3-Dioxygenase (IDO) inhibitor, also is a potent H1N1 neuraminidase (NA-1) inhibitor with an IC50 of 104.6 μg/mL, also is a novel METTL3 inhibitor and performs therapeutic effect on periodontitis. |