MEK(MAP2K) (inhibitors, antagonists, agonists)-ProbeChem.com

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Cat. No.	Product Name	Information
PC-63100	WX-554	WX-554 is an oral, small molecule allosteric inhibitor targeting mitogen-activated protein kinase kinase (MEK1 and MEK2) with an estimated IC50 of 4.7 and 10.7 nM, respectively.
PC-61420	Etacrynic acid	A loop diuretic used to treat high blood pressure and the swelling, a novel ligand and inhibitor of MAP2K6 kinase that inhibits MAP2K6 in part through alkylation of a nonconserved cysteine residue.
PC-42462	Refametinib R enantiomer	The R enantiomer of Refametinib, a potent, non–ATP-competitive, highly selective, allosteric inhibitor of MEK1/2 with IC50 of 19/47 nM respectively..
PC-42775	Trametinib DMSO solvate	A potent and highly specific MEK1/2 inhibitor with IC50 of 0.92 nM/1.8 nM.

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