| Cat. No. |
Product Name |
Information |
| PC-49588 |
AZD0095
MCT4 inhibitor
|
AZD0095 (AZD-0095) is a potent, selective monocarboxylate transporter 4 (MCT4) inhibitor with IC50 of 1.3 nM, >1000-fold selectivity over MCT1. |
| PC-49038 |
MCT4 inhibitor CB-2
MCT4 inhibitor
|
MCT4 inhibitor CB-2 is a novel small molecule MCT4 inhibitor with significantly inhibitory effect on lactate secretion and striking cytotoxic activity against MDA‐MB‐231 cells. |
| PC-72709 |
MSC-4381
MCT4 inhibitor
|
MSC-4381 (MCT4 inhibitor 18n) is a potent, selective inhibitor of monocarboxylate transporter 4 (MCT4/SLC16A3). |
| PC-38048 |
VB124
MCT4 inhibitor
|
VB124 is a selective, highly potent MCT4 inhibitor, blocks lactate import (IC50 =8.6 nM) and export (IC50=19 nM) in MDA-MB-231 cells. |
| PC-35589 |
BAY-8002
MCT1 inhibitor
|
BAY-8002 is a novel potent, selective, orally available monocarboxylate transporter 1 (MCT1) inhibitor (Kd=7.9 nM), inhibits cellular lactate uptake in DLD-1 cells with IC50 of 8 nM. |
| PC-63259 |
7ACC2
MCT inhibitor
|
7ACC2 is a potent inhibitor of mitochondrial pyruvate transport (MPC) and monocarboxylate transporter (MCT) with IC50 of 11 nM for inhibition of [14C]-lactate influx, consecutively blocks extracellular lactate uptake by promoting intracellular pyruvate accumulation. |
| PC-43427 |
AR-C155858
MCT1/MCT2 inhibitor
|
AR-C155858 is a potent monocarboxylate transporter MCT1 and MCT2 with Ki of 2.3 nM and <10 nM, displays no activity at MCT4. |
| PC-43178 |
AZD3965
MCT1 inhibitor
|
AZD3965 (AZD-3965) is a potent, selective, orally bioavailable monocarboxylate transporter 1 (MCT1) inhibitor with binding IC50 of 1.6 nM, displays 6-fold selectivity over MCT2 and does not inhibit MCT3 or MCT4. |
| PC-22036 |
Lactate transport compound 1
|
Lactate transport compound 1 is a small molecule lactate transmembrane carrier and cell-active lactate transporter, facilitates lactate transport across phospholipid membranes in model liposomes and cells, sensitizes cancer cells against chemotherapy cisplatin in HeLa cells. |
| PC-20896 |
slCeMM1
MCT4 inhibitor
|
slCeMM1 is a potent, highly selective inhibitor of lactate transporter SLC16A3 (MCT4), inhibits intracellular lactate accumulation in SLC16A3 dependent cells (IC50=91 nM). |
| PC-62725 |
MCT1-IN-4a
|
MCT1-IN-4a is a potent, selective monocarboxylate transporter 1 (MCT1) inhibitor with IC50 of 90 nM. |
