| Cat. No. |
Product Name |
Information |
| PC-38622 |
SHA68
NPSR antagonist
|
SHA68 is a selective non-peptide neuropeptide S receptor (NPSR) antagonist with IC50 of 22.0 and 23.8 nM for human NPSR Asn107 and Ile107 variants respectively, Ke value of 13.7 nM (Ile107 variant). |
| PC-38604 |
NPY5RA-972
NPY5R antagonist
|
NPY5RA-972 is a potent, highly selective, orally active, and CNS-penetrant neuropeptide Y5 receptor (NPY5) antagonist with IC50 of 3.1 nM, highly selective with respect to Y1, Y2, and Y4 receptors. |
| PC-38252 |
BIIE0246
NPY2R antagonist
|
BIIE0246 (BIIE 0246) is a potent, highly selective non-peptide neuropeptide Y Y2 receptor antagonist with IC50 of 15 nM, >650-fold selectivity over Y1, Y4 and Y5 receptors. |
| PC-35865 |
AC-263093
NPFFR2 agonist
|
AC-263093 (AC263093) is a potent, functionally selective neuropeptide FF receptor type 2 (NPFFR2) agonist with pKi of 6.9. |
| PC-62525 |
BIBO3304
NPY1R antagonist
|
BIBO3304 is a potent, selective, nonpeptide neuropeptide Y Y1 receptor (NPY1R) antagonist with IC50 of 0.38 and 0.72 nM for human and the rat Y1 receptor, respectively. |
| PC-61061 |
tBPC
Y4R PAM
|
tBPC is a potent, selective neuropeptide Y (NPY) receptor Y4R positive allosteric modulator (EC50=5.1 uM) that potentiates Y4R activation in G-protein signaling and arrestin3 recruitment experiments. |
| PC-23613 |
Hederagenin
NPFFR1 antagonist
|
Hederagenin is a triterpenoid saponin with antitumor activity against multifarious cancers, is a selective antagonist of neuropeptide FF receptor 1 (NPFFR1), selectively inhibits activation of NPFFR1 by NPFF or NPVF through orthosteric antagonism. |
| PC-23085 |
Nisotirostide
NPY receptor agonist
|
Nisotirotide (LY-3457263) is a gut hormone peptide YY (PYY) analog and Neuropeptide Y receptor (NPY receptor) agonist. |
| PC-20970 |
VU0506013
Y4R PAM
|
VU0506013 is a high-affinity, selective positive allosteric modulator (PAM) of neuropeptide Y4 receptor (Y4R) with EC50 of 125 nM. |
