Cat. No. |
Product Name |
Information |
PC-45701 |
BMS-202
|
BMS-202 (PCC0208025) is a small molecule inhibitor of the PD-1/PD-L1 interaction with IC50 of 18 nM in a homogenous time-resolved fluorescence binding assay. |
PC-45776 |
PD1-PDL1 inhibitor 1
|
PD1-PDL1 inhibitor 1 (CAS 1675201-83-8) is a potent PD-1/PD-L1 interaction inhibitor with IC50 of 6-100 nM in a homogenous time-resolved fluorescence binding assay.. |
PC-21925 |
SMC18
PD-L1 inhibitor
|
SMC18 is a specific small molecule CD47/SIRPα and PD-1/PD-L1 dual inhibitor, effectively blocks the CD47/SIRPα and PD-1/PD-L1 interactions with IC50 of 17.8 and 19.7 uM (human SIRPα and hPD-L1) respectively. |
PC-20282 |
YPD-29B
PD-L1 inhibitor
|
YPD-29B is a potent, specific programmed cell death ligand 1 (PD-L1) inhibitor, effectively blocks the binding of PD-1 and PD-L1 with IC50 of 0.08 pM in HTRF protein-protein interaction assays. |
PC-20281 |
IMMH-010
PD-L1 inhibitor
|
IMMH-010 (YPD-30) is an ester prodrug of YPD-29B, a high potent PD-L1 inhibitor (IC50=0.08 pM), YPD-30 is a potent PD-L1 inhibitor with IC50 of 45.2 nM in HTRF assays. |
PC-20280 |
IMMH-010 maleate
PD-L1 inhibitor
|
IMMH-010 maleate (YPD-30) is an ester prodrug of YPD-29B, a high potent PD-L1 inhibitor (IC50=0.08 pM), YPD-30 is a potent PD-L1 inhibitor with IC50 of 45.2 nM in HTRF assays. |
PC-20279 |
MAX10181
PD-L1 inhibitor
|
MAX10181 (MAX-10181) is an orally active small molecule PD-L1 inhibitor, shows similar efficacy as Durvalumab in the head to head test of human PD-L1 knock-in MC38 cell line in human PD-1 knock-in mice. |
PC-49504 |
PD-L1 inhibitor S4-1
PD-L1 inhibitor
|
PD-L1 inhibitor S4-1 is a novel small-molecule inhibitor of PD-L1, effectively alters the PD-L1/PD-1 interaction, induces PD-L1 dimerization and internalization. |
PC-49402 |
PD-1 inhibitor SCL-1
PD-1 inhibitor
|
PD-1 inhibitor SCL-1 is a potent small molecule inhibitor of PD-1/PD-L1 binding and exerts potent antitumor effects. |
PC-49098 |
BMS136
PD-L1 inhibitor
|
BMS136 is a small molecule h-PD1/h-PD-L1 interaction inhibitor with IC50 of 96.7 nM, bind specifically to hPD-L1 through a unique mode of action, induces the dimerization of hPD-L1. |
PC-72493 |
ARB-272572
PD-L1 inhibitor
|
ARB-272572 (ARB272572, Compound A) is a potent small-molecule PD-L1 inhibitor, inhibits PD-1/PD-L1 with HTRF IC50 of 0.4 nM. |
PC-35694 |
AUNP-12
|
AUNP-12 (Aurigene-012) is a PD-1 inhibitor peptide, blocks the PD-1/PD-L1, PD-1/PD-L2 and PD-L1/CD80 pathways. |