| Cat. No. |
Product Name |
Information |
| PC-20572 |
Ceefourin-1
MRP4/ABCC4 inhibitor
|
Ceefourin-1 is a highly selective inhibitor of multidrug resistance protein 4 (MRP4/ABCC4), inhibits the efflux of a broad range of MRP4 substrates. |
| PC-73219 |
Encequidar mesylate monohydrate
MDR1 inhibitor
|
Encequidar (HM30181) mesylate monohydrate is a potent selective inhibitor of MDR1 (ABCB1, P-gp) with IC50 of 0.63 nM. |
| PC-73218 |
Encequidar
MDR1 inhibitor
|
Encequidar (HM30181) is a potent selective inhibitor of MDR1 (ABCB1, P-gp) with IC50 of 0.63 nM. |
| PC-72608 |
CP-100356 hydrochloride
P-gp inhibitor
|
CP-100356 hydrochloride (CP100356) is a specific P-glycoprotein (P-gp) inhibitor, suppresses VSV-LASVGP, LCMV, and LASV infection with IC50 of 0.52, 0.54, and 0.062 uM, respectively, without significant cytotoxicity. |
| PC-62666 |
NSC23925B
P-gp inhibitor
|
NSC23925B is a small molecule agent that reverses MDR in cancer cells, reverses MDR in several drug-resistant cell lines expressing P-gp. |
| PC-62665 |
NSC23925
P-gp inhibitor
|
NSC 23925 is a small molecule compound that reverses multiple drug resistance (MDR) in human cancer cell lines, reverses MDR1 (Pgp1) but does not inhibit MRP or BCRP-mediated MDR. |
| PC-70022 |
Laniquidar
P-gp inhibitor
|
Laniquidar (R101933) is an orally active, third-generation P-glycoprotein inhibitor that inhibits the drug efflux pump P-glycoprotein, resulting in higher concentrations of antineoplastic agents in tumor cells that are multi-drug resistant due to the overexpression of P-glycoprotein. |
| PC-42648 |
Tariquidar
P-gp inhibitor
|
Tariquidar (XR9576) is a potent, specific P-gp inhibitor with Kd of 5.1 nM. |
| PC-45836 |
Zosuquidar trihydrochloride
P-gp inhibitor
|
Zosuquidar trihydrochloride (LY-335979) is a potent P-glycoprotein (P-gp) inhibitor with Ki of 60 nM. |
| PC-45888 |
Elacridar hydrochloride
P-gp inhibitor
|
Elacridar hydrochloride is a potent inhibitor of multidrug resistance (MDR, P-gp) that fully reverses multidrug resistance CHRC5, OV1/DXR and MCF7/ADR cells to the cytotoxicity of doxorubicin and vincristine with IC50 of 0.02 uM. |
| PC-45887 |
Elacridar
P-gp inhibitor
|
Elacridar (GF120918, GW-0918) is a potent inhibitor of multidrug resistance (MDR, P-gp) that fully reverses multidrug resistance CHRC5, OV1/DXR and MCF7/ADR cells to the cytotoxicity of doxorubicin and vincristine with IC50 of 0.02 uM. |
| PC-45137 |
Dofequidar fumarate
P-gp inhibitor
|
Dofequidar fumarate (MS-209) is an orally active quinoline compound that can reverse P-glycoprotein (P-gp)-mediated MDR. |
