| Cat. No. |
Product Name |
Information |
| PC-62457 |
XR 5118
PAI-1 inhibitor
|
XR5118 is a small molecule plasminogen activator inhibitor-1 (PAI-1) inhibitor with IC50 of 3.5 uM, binds to PAI-1 and reduces plasma PAI-1 activity levels, promotes endogenous thrombolysis and inhibits thrombus accretion. |
| PC-61650 |
SK-216
PAI-1 inhibitor
|
SK-216 is a potent, selective inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 of 44 uM. |
| PC-70342 |
CDE 096
PAI-1 inhibitor
|
CDE 096 (CDE-096, CDE096) is a selective, reversible, high-affinity PAI-1 inhibitor that prevents PAI-1 from inactivating tPA and uPA with similar potency (IC50=30 and 25 nM, respectively). |
| PC-60844 |
TM5275
PAI-1 inhibitor
|
TM-5275 (TM5275) is a potent, orally active PAI-1 (plasminogen activator inhibitor-1) inhibitor with IC50 of 6.95 uM. |
| PC-42144 |
WX-UK1
uPA inhibitor
|
WX-UK1 (UKI-1) is a small synthetic serine protease uPA (urokinase-type plasminogen activator) inhibitor that blocks tumor cell invasion, metastasis and primary tumor growth. |
| PC-42335 |
UK-371804
uPA inhibitor
|
UK-371804 is a potent and selective inhibitor of urokinase-type plasminogen activator (uPA) with Ki of 10 nM. |
| PC-24263 |
Tranexamic acid
uPA inhibitor
|
Tranexamic acid (Cyclocapron) is a cyclic analog of lysine and orally active antifibrinolytic agent, inhibits urokinase plasminogen activator (uPA) and ameliorates dry wrinkles, attenuates the effects of severe trauma. |
| PC-24262 |
BT-114143
Plasminogen activation inhibitor
|
BT-114143 is a small molecule plasminogen activation inhibitor with IC50 of 7.42 uM in in vitro enzymatic reaction system (buffer clot lysis assay), and IC50 of 0.56 uM for fibrinolysis in human whole blood. |
| PC-22552 |
TM5614 sodium
PAI-1 inhibitor
|
TM5614 sodium is a specific PAI-1 inhibitor with an IC50 value of 3.63 μM in a tPA-dependent hydrolysis assay. |
| PC-22551 |
TM5614
PAI-1 inhibitor
|
TM5614 is a specific PAI-1 inhibitor with an IC50 value of 3.63 μM in a tPA-dependent hydrolysis assay. |
| PC-21332 |
TM5441
PAI-1 inhibitor
|
TM5441 is a specific, orally active, small molecule inhibitor of plasminogen activator inhibitor 1 (PAI-1, Serpin E1), TM5441 is as effective as complete deficiency of PAI-1 in protecting against L-NAME-induced pathologies. |
