| Cat. No. |
Product Name |
Information |
| PC-70342 |
CDE 096
PAI-1 inhibitor
|
CDE 096 (CDE-096, CDE096) is a selective, reversible, high-affinity PAI-1 inhibitor that prevents PAI-1 from inactivating tPA and uPA with similar potency (IC50=30 and 25 nM, respectively). |
| PC-60844 |
TM5275
PAI-1 inhibitor
|
TM-5275 (TM5275) is a potent, orally active PAI-1 (plasminogen activator inhibitor-1) inhibitor with IC50 of 6.95 uM. |
| PC-42144 |
WX-UK1
uPA inhibitor
|
WX-UK1 (UKI-1) is a small synthetic serine protease uPA (urokinase-type plasminogen activator) inhibitor that blocks tumor cell invasion, metastasis and primary tumor growth. |
| PC-42335 |
UK-371804
uPA inhibitor
|
UK-371804 is a potent and selective inhibitor of urokinase-type plasminogen activator (uPA) with Ki of 10 nM. |
| PC-22552 |
TM5614 sodium
PAI-1 inhibitor
|
TM5614 sodium is a specific PAI-1 inhibitor with an IC50 value of 3.63 μM in a tPA-dependent hydrolysis assay. |
| PC-22551 |
TM5614
PAI-1 inhibitor
|
TM5614 is a specific PAI-1 inhibitor with an IC50 value of 3.63 μM in a tPA-dependent hydrolysis assay. |
| PC-21332 |
TM5441
PAI-1 inhibitor
|
TM5441 is a specific, orally active, small molecule inhibitor of plasminogen activator inhibitor 1 (PAI-1, Serpin E1), TM5441 is as effective as complete deficiency of PAI-1 in protecting against L-NAME-induced pathologies. |
| PC-49769 |
Diaplasinin
PAI-1 inhibitor
|
Diaplasinin (PAI-749) is a potent, selective antagonist of plasminogen activator inhibitor 1 (PAI-1) with IC50 of 154 nM (preservation of tPA activity) and Ki of 253 nM, blocks PAI-1 mediated inhibition of uPA with IC50 of 87 nM. |
| PC-49768 |
Tiplaxtinin
PAI-1 inhibitor
|
Tiplaxtinin (PAI-039) is a selective, orally active plasminogen activator inhibitor-1 (PAI-1) inhibitor with IC50 of 2.7 uM and Kd of 0.48 uM. |
