| Cat. No. |
Product Name |
Information |
| PC-35871 |
MDI-2268
PAI-1 inhibitor
|
MDI-2268 (MDI2268) is a small-molecule, in vivo-active inhibitor of plasminogen activator inhibitor type-1 (PAI-1), demonstrates excellent pharmacokinetics, potent activity against vitronectin-bound PAI-1 in vivo, and efficacy in murine model of venous thrombosis. |
| PC-35664 |
ZK824859
uPA inhibitor
|
ZK824859 (ZK-824859) is a potent, selective urokinase plasminogen activator (uPA) inhibitor with IC50 of 79 nM (human uPA), displays little to no inhibitory activity against tPA and Plasmin (IC50>1 uM). |
| PC-35440 |
Cenupatide
uPA inhibitor
|
Cenupatide is an urokinase plasminogen activator receptor (uPAR) inhibitor for treating disorders associated altered cell migration, such as cancer.. |
| PC-35131 |
TM5007
PAI-1 inhibitor
|
TM5007 is a poent inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 of 29 uM, exhibits no inhibitory activity against any of the closely related serpins or serine proteases at 250 uM. |
| PC-62457 |
XR 5118
PAI-1 inhibitor
|
XR5118 is a small molecule plasminogen activator inhibitor-1 (PAI-1) inhibitor with IC50 of 3.5 uM, binds to PAI-1 and reduces plasma PAI-1 activity levels, promotes endogenous thrombolysis and inhibits thrombus accretion. |
| PC-61650 |
SK-216
PAI-1 inhibitor
|
SK-216 is a potent, selective inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 of 44 uM. |
| PC-70342 |
CDE 096
PAI-1 inhibitor
|
CDE 096 (CDE-096, CDE096) is a selective, reversible, high-affinity PAI-1 inhibitor that prevents PAI-1 from inactivating tPA and uPA with similar potency (IC50=30 and 25 nM, respectively). |
| PC-60844 |
TM5275
PAI-1 inhibitor
|
TM-5275 (TM5275) is a potent, orally active PAI-1 (plasminogen activator inhibitor-1) inhibitor with IC50 of 6.95 uM. |
| PC-42144 |
WX-UK1
uPA inhibitor
|
WX-UK1 (UKI-1) is a small synthetic serine protease uPA (urokinase-type plasminogen activator) inhibitor that blocks tumor cell invasion, metastasis and primary tumor growth. |
| PC-42335 |
UK-371804
uPA inhibitor
|
UK-371804 is a potent and selective inhibitor of urokinase-type plasminogen activator (uPA) with Ki of 10 nM. |
| PC-25190 |
UK-356,202
uPA inhibitor
|
UK-356,202 (UK356202) is a potent, selective urokinase-type plasminogen activator (uPA) inhibitor with Ki of 37 nM, with no acitvity against tPA and Plasmin. |
| PC-24263 |
Tranexamic acid
uPA inhibitor
|
Tranexamic acid (Cyclocapron) is a cyclic analog of lysine and orally active antifibrinolytic agent, inhibits urokinase plasminogen activator (uPA) and ameliorates dry wrinkles, attenuates the effects of severe trauma. |
