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Cat. No. Product Name Information
PC-49720

AA132

UPR activator

AA132 (AA-132) is a small molecule activator of UPR signaling, covalently modifies a subset of ER protein disulfide isomerases (PDIs), activates global UPR signaling through a mechanism analogous to that of AA147.
PC-63459

KSC-34

PDIA1 inhibitor

KSC-34 (PDIA1 inhibitor KSC-34) is a potent, selective protein disulfide isomerase A1 (PDIA1) inhibitor, 30-fold selectivity for the A-site over the A' site.
PC-62115

ML359

PDI inhibitor

ML359 is a small molecule, specific inhibitor of Protein disulfide isomerase (PDI) with IC50 of 250 nM.
PC-62113

Juniferdin

PDI inhibitor

Juniferdin is a small molecule, potent Protein disulfide isomerase (PDI) inhibitor with IC50 of 156 nM, inhibits PDI-mediated reduction of HIV-1 envelope glycoprotein gp120.
PC-61520

16F16

PDI inhibitor

16F16 is a small molecule protein disulfide isomerase (PDI) inhibitor that suppress apoptosis induced by misfolded proteins.
PC-70360

PACMA31

PDI inhibitor

PACMA31 is an orally active, irreversible inhibitor of protein disulfide isomerase (PDI), forming a covalent bond with the active site cysteines of PDI.
PC-70321

LOC14

PDI inhibitor

LOC14 is a small molecule reversible Protein disulfide isomerase (PDI) inhibitor with Kd of 62 nM.
PC-42153

CCF642

PDI inhibitor

CCF642 (CCF 642) is a novel covalent protein disulfide isomerase (PDI) inhibitor with IC50 of 2.9 uM, shows antimyeloma activity.
PC-21467

E64FC26

pan PDI inhibitor

E64FC26 is a potent, pan-style PDI (protein disulfide isomerase) inhibitor with IC50 of 1.9 uM (PDIA1), also inhibits all other members of the PDI family including PDIA3, PDIA4, TXNDC5, and PDIA6.

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