Raf (inhibitors, antagonists, agonists)-ProbeChem.com

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Cat. No.	Product Name	Information
PC-24277	Braftide RAF dimerization inhibitor	Braftide is a potent allosteric RAF kinase dimer disruptor, inhibits RAF dimerization by targeting the conserved RAF dimer interface, inhibits wild-type BRAF and oncogenic BRAF G469A with IC50 of 364 nM and 172 nM, respectively.
PC-21593	Erianin Raf-MEK inhibitor	Erianin is a small molecule inhibitor of CRAF and MEK1/2 kinases, inhibits constitutive activation of MAPK signaling pathway.
PC-21592	SHR902275 RAFinhibitor	SHR902275 is a potent, selective, and orally active RAF inhibitor targeting RAS mutants with IC50 of 1.6 nM, 10 nM, and 5.7 nM for cRAF, bRAFwt, and bRAFV600E, respectively.

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