| Cat. No. |
Product Name |
Information |
| PC-60905 |
MBQ-167
Rac/Cdc42 inhibitor
|
MBQ-167 (MBQ 167, MBQ167) is a potent, dual Rac/Cdc42 inhibitor with IC50 of 103/78 nM, respectively, in metastatic breast cancer cells. |
| PC-60847 |
Nexinhib20
Rab27a-JFC1 inhibitor
|
Nexinhib20 is a specific small molecule neutrophil exocytosis inhibitor (IC50=0.33 uM) that specifically inhibits Rab27a-JFC1 binding (IC50=2.6 uM) but does not interfere with the interaction of other Rab GTPases and effectors. |
| PC-60611 |
NAV-2729
ARF6 inhibitor
|
NAV-2729 (NAV2729) is a novel, direct and selective small molecule inhibitor of small GTPase ARF6 with IC50 of 1.5 uM in nucleotide exchange assays. |
| PC-44661 |
NSC 23766 trihydrochloride
Rac inhibitor
|
NSC 23766 trihydrochloride is a specific small molecule inhibitor of Rac GTPase. |
| PC-44660 |
NSC 23766
Rac inhibitor
|
NSC 23766 (NSC23766) is a specific small molecule inhibitor of Rac GTPase.
|
| PC-43811 |
ZCL278
Cdc42 inhibitor
|
ZCL278 is a potent, cell-permeable Cdc42-specific small-molecule inhibitor (Kd=6.4 uM). |
| PC-28592 |
ACR-917
RhoA inhibitor
|
ACR-917 is a covalent small molecule inhibitor of Rho family GTPase RhoA protein by covalent modification of Cys107, inhibits RhoA C190S nucleotide exchange with IC50 of 46 uM. |
| PC-28591 |
ACR-895
RhoA inhibitor
|
ACR-895 is a covalent small molecule inhibitor of Rho family GTPase RhoA protein by covalent modification of Cys107, inhibits RhoA C190S nucleotide exchange with IC50 of 20 uM. |
| PC-28589 |
DC-Rhoin
RhoA inhibitor
|
DC‐Rhoin (DC-RC-063) is a selective, covalent small molecule inhibitor of Rho family GTPase RhoA protein, inhibits GDP/GTP exchange rate of RhoA with IC50 of 2.94 uM. |
| PC-28588 |
RhoA-ROCK-IN-1
RhoA inhibitor
|
RhoA/ROCK-IN-1 (Compound b19) is a small molecule RhoA/ROCK pathway inhibitor, has anti-proliferative activity on A549 cells with IC50 of 4.8 uM, significantly inhibits the proliferation, migration, and invasion of MDA-MB-231 cells and promotes apoptosis. |
| PC-27402 |
Acmiribine
Rac1 inhibitor
|
Acmiribine (8-Hydroxy-2-deoxyguanosine, 8-OHdG) is a small molecule Rac1 inhibitor, suppresses NO production and COX-2 activity via Rac1/STATs signaling in LPS-induced brain microglia. |
| PC-26767 |
(R)-Ketorolac
Cdc42/Rac1 inhibitor
|
(R)-Ketorolac (R-ketorolac) is a small molecule allosteric Cdc42 and Rac1 GTPases inhibitor, significantly inhibits cell adhesion, migration and invasion in ovarian cancer cells. |
