| Cat. No. |
Product Name |
Information |
| PC-22521 |
ARN24928
Cdc42 inhibitor
|
ARN24928 is a potent, selective inhibitor of CDC42 GTPases (CDC42, RHOJ, RHOQ), exhibits s antiproliferative activity of melanoma cancer cell lines that have a BRAFV600E mutation (SKM28, SKMel3, WM3248, A375) with IC50 of 3.2-6.9 uM. |
| PC-22520 |
ARN25499
Cdc42 inhibitor
|
ARN25499 is a potent, selective inhibitor of CDC42 GTPases (CDC42, RHOJ, RHOQ), exhibits s antiproliferative activity of melanoma cancer cell lines that have a BRAFV600E mutation (SKM28, SKMel3, WM3248, A375) with IC50 of 8-13.5 uM. |
| PC-20183 |
GYS32661
RAC1 inhibitor
|
GYS32661 (GYS 32661) is a potent Rac inhibitor capable of inhibiting both Rac1 and Rac1b, inhibited activated Rac1 with IC50 of 1.18 uM in in vitro pull-down assays. |
| PC-20011 |
Rho GTPase inhibitor O1
Rho inhibitor
|
Rho GTPase inhibitor O1 is a small molecule RhoA GTPase inhibitor, perturbs mitotic progression in fission yeast. |
| PC-38721 |
1D-142
RAC1 inhibitor
|
1D-142 is a novel small molecule RHO family of GTPase RAC1 inhibitor, inhibits Rac1-GEF interaction and reduces Rac1-mediated TNFα-induced NF-κB nuclear translocation during cell proliferation and migration. |
| PC-38507 |
RBC10
Ral GTPase inhibitor
|
RBC10 is a small molecule that target the Ral GTPase, inhibits Ral binding to its effector RalBP1, Ral-mediated cell spreading in murine fibroblasts and anchorage-independent growth of human cancer cell lines. |
