| Cat. No. |
Product Name |
Information |
| PC-61174 |
SecinH3
Cytohesin GEFs inhibitor
|
SecinH3 is a selective inhibitor of small GEFs of the cytohesin family, blocks human, mouse and Drosophila cytohesins with IC50 of 2.4 to 5.6 uM. |
| PC-60905 |
MBQ-167
Rac/Cdc42 inhibitor
|
MBQ-167 (MBQ 167, MBQ167) is a potent, dual Rac/Cdc42 inhibitor with IC50 of 103/78 nM, respectively, in metastatic breast cancer cells. |
| PC-60847 |
Nexinhib20
Rab27a-JFC1 inhibitor
|
Nexinhib20 is a specific small molecule neutrophil exocytosis inhibitor (IC50=0.33 uM) that specifically inhibits Rab27a-JFC1 binding (IC50=2.6 uM) but does not interfere with the interaction of other Rab GTPases and effectors. |
| PC-60611 |
NAV-2729
ARF6 inhibitor
|
NAV-2729 (NAV2729) is a novel, direct and selective small molecule inhibitor of small GTPase ARF6 with IC50 of 1.5 uM in nucleotide exchange assays. |
| PC-44661 |
NSC 23766 trihydrochloride
Rac inhibitor
|
NSC 23766 trihydrochloride is a specific small molecule inhibitor of Rac GTPase. |
| PC-44660 |
NSC 23766
Rac inhibitor
|
NSC 23766 (NSC23766) is a specific small molecule inhibitor of Rac GTPase.
|
| PC-43811 |
ZCL278
Cdc42 inhibitor
|
ZCL278 is a potent, cell-permeable Cdc42-specific small-molecule inhibitor (Kd=6.4 uM). |
| PC-25791 |
(6R)-HR3119
RhoGDI2 inhibitor
|
(6R)-HR3119 is a small molecule ligand of Guanine nucleotide dissociation inhibitors (GDIs) protein RhoGDI2 with low-micromolar affinity (Kd= 4 uM), engages with RhoGDI2 in cells and suppresses the migration of aggressive breast cancer cells. |
| PC-25187 |
Rac1 Inhibitor W56
RAC1 inhibitor
|
Rac1 Inhibitor W56 is a peptide inhibitor of Rac1 containing residues 45-60 of Rac1, inhibits Rac1 interaction with guanine nucleotide exchange factors TrioN, GEF-H1, and Tiam. |
| PC-24534 |
MLS-573151
Cdc42 inhibitor
|
MLS-573151 (MLS000573151) is a specific small molecule inhibitor of GTPase Cdc42 with EC50 of 2 uM, selective over other Rho family GTPases, including Rac1, Rac 2, RhoA. |
| PC-23016 |
DU102
Arf1 inhibitor
|
DU102 is a potent small molecule inhibitor of small G protein Arf1, binds to the catalytic pocket of the Arf1-GDP-Sec7, inhibit Arf1 activity by binding to Arf1 and Arf-GEF. |
| PC-23015 |
DU101
Arf1 inhibitor
|
DU101 is a potent small molecule inhibitor of small G protein Arf1, binds to the catalytic pocket of the Arf1-GDP-Sec7, inhibit Arf1 activity by binding to Arf1 and Arf-GEF. |
