p21-activated Kinase (PAK) compound (inhibitors, antagonists, modulators)-ProbeChem.com

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Cat. No.	Product Name	Information
PC-62720	GNE-2861 group II PAK inhibitor	GNE-2861 is a potent, selective group II PAK (PAK4/5/6) inhibitor with IC50 of 7.5/126/36 nM, respectively, shows selectivity over group I PAKs (IC50=5.42/0.97/>10 uM for PAK1/2/3).
PC-62552	IPP-14 PAK1-PUMA inhibitor	IPP-14 is a novel PAK1 inhibitor that selectively blocks the PAK1-PUMA binding and suppresses cell proliferation via PUMA-dependent manner.
PC-60221	G-9791 group I PAK inhibitor	G-9791 (G9791) is a potent and selective group I PAK (pan-PAK1/2/3) inhibitor with Ki of 0.95/2 nM for PAK1/2, respectively.
PC-45665	G-5555 PAK1 inhibitor	G-5555 is a potent and selective p21-activated kinase 1 (PAK1) inhibitor (Ki=3.7 nM).
PC-45644	FRAX-1036 PAK inhibitor	FRAX1036 is a potent and selective inhibitor of group I PAKs (PAK1, Ki=23.3 nM; PAK2, Ki=72.4 nM).
PC-46979	Hydrastine PAK4 inhibitor	An alkaloid of Hydrastis canadensis used in many dietary supplements intended to enhance the immune system.
PC-44510	FRAX597 PAK inhibitor	FRAX597 is a potent, selective ATP-competitive inhibitor of group I PAKs with IC50 of 8/13/19 nM for PAK1/2/3.

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