| Cat. No. |
Product Name |
Information |
| PC-62720 |
GNE-2861
group II PAK inhibitor
|
GNE-2861 is a potent, selective group II PAK (PAK4/5/6) inhibitor with IC50 of 7.5/126/36 nM, respectively, shows selectivity over group I PAKs (IC50=5.42/0.97/>10 uM for PAK1/2/3). |
| PC-62552 |
IPP-14
PAK1-PUMA inhibitor
|
IPP-14 is a novel PAK1 inhibitor that selectively blocks the PAK1-PUMA binding and suppresses cell proliferation via PUMA-dependent manner. |
| PC-60221 |
G-9791
group I PAK inhibitor
|
G-9791 (G9791) is a potent and selective group I PAK (pan-PAK1/2/3) inhibitor with Ki of 0.95/2 nM for PAK1/2, respectively. |
| PC-45665 |
G-5555
PAK1 inhibitor
|
G-5555 is a potent and selective p21-activated kinase 1 (PAK1) inhibitor (Ki=3.7 nM). |
| PC-45644 |
FRAX-1036
PAK inhibitor
|
FRAX1036 is a potent and selective inhibitor of group I PAKs (PAK1, Ki=23.3 nM; PAK2, Ki=72.4 nM). |
| PC-46979 |
Hydrastine
PAK4 inhibitor
|
An alkaloid of Hydrastis canadensis used in many dietary supplements intended to enhance the immune system. |
| PC-44510 |
FRAX597
PAK inhibitor
|
FRAX597 is a potent, selective ATP-competitive inhibitor of group I PAKs with IC50 of 8/13/19 nM for PAK1/2/3. |
