| Cat. No. |
Product Name |
Information |
| PC-38860 |
IK-175
AhR inhibitor
|
IK-175 is a potent, selective and orally active aryl hydrocarbon receptor (AHR) antagonist with IC50 of 91 nM in human HepG2 cells expressing an AHR-dependent DRE-luciferase reporter and stimulated with 80 nM of the AHR agonist VAF347. |
| PC-38597 |
KYN-101
AhR antagonist
|
KYN-101 (KYN101) is a potent, selective synthetic antagonist of aryl hydrocarbon receptor (AHR) with IC50 of 22 nM in human HepG2 DRE-luciferase reporter assay and 23 nM in murine Hepa1 Cyp-luc assay. |
| PC-38513 |
SGA360
AhR modulator
|
SGA360 is a high-affinity, selective modulator of aryl hydrocarbon receptor (AhR), competitively binds to AhR (IC50 =3 uM) and represses serum amyloid A 1 (SAA1) gene expression induced by IL-1β in Huh7 cells. |
| PC-38065 |
BAY2416964
AHR antagonist
|
BAY2416964 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist with IC50 of 341 nM. |
| PC-43148 |
CH-223191
AhR antagonist
|
CH-223191 is a potent, specific antagonist of AhR (aryl hydrocarbon receptor), potently inhibits TCDD-induced AhR-dependent transcription with IC50 of 0.03 uM. |
| PC-61627 |
FICZ
AhR agonist
|
FICZ is a high affinity aryl hydrocarbon receptor (AhR) agonist with Kd of 70 pM. |
| PC-60777 |
Phortress
AhR agonist
|
Phortress (NSC710305) is the L-lysylamide prodrug of 5F-203 (NSC703786), a potent, selective antitumour agent through activation the aryl hydrocarbon receptor (AhR) pathway. |
| PC-60776 |
5F-203
AhR agonist
|
5F 203 (NSC 703786) is a potent, selective antitumour agent through activation the aryl hydrocarbon receptor (AhR) pathway. |
| PC-60775 |
NK150460
AhR agonist
|
NK150460 is a potent and selective inhibitor of breast cancer cells via activation the aryl hydrocarbon receptor (AhR) pathway. |
| PC-60774 |
ANI-7
AhR agonist
|
ANI-7 is a potent and selective (up to 263-fold) inhibitor of breast cancer cells with GI50 of 0.5 uM (MCF-7), via activation the aryl hydrocarbon receptor (AhR) pathway. |
| PC-60390 |
GNF-351
AhR antagonist
|
GNF-351 is a potent, pure aryl hydrocarbon receptor (AHR) antagonist (IC50=62 nM) devoid of partial agonist potential. |
| PC-60054 |
Benvitimod
AhR agonist
|
Benvitimod (GSK-2894512, Tapinarof) is a natural aryl hydrocarbon receptor (AhR) agonist with anti-inflammatory properties. |
