| Cat. No. |
Product Name |
Information |
| PC-60774 |
ANI-7
AhR agonist
|
ANI-7 is a potent and selective (up to 263-fold) inhibitor of breast cancer cells with GI50 of 0.5 uM (MCF-7), via activation the aryl hydrocarbon receptor (AhR) pathway. |
| PC-60390 |
GNF-351
AhR antagonist
|
GNF-351 is a potent, pure aryl hydrocarbon receptor (AHR) antagonist (IC50=62 nM) devoid of partial agonist potential. |
| PC-60054 |
Benvitimod
AhR agonist
|
Benvitimod (GSK-2894512, Tapinarof) is a natural aryl hydrocarbon receptor (AhR) agonist with anti-inflammatory properties. |
| PC-45600 |
AhR agonist ITE
AhR agonist
|
AhR agonist ITE is a endogenous ligand, potent aryl hydrocarbon receptor (AhR) agonist in vitro and in vivo. |
| PC-26733 |
PM-4321
AhR antagonist
|
PM-4321 is a potent, selective aryl hydrocarbon receptor (AhR) modulator profiled as part of an AhR antagonist, inhibits TCDD-induced AhR activation with IC50 of 2 nM. |
| PC-26676 |
CB7993113
AHR antagonist
|
CB7993113 is a potent, selective aryl hydrocarbon receptor (AhR) antagonist, blocks DMBA-induced AHR-dependent reporter activity with IC50 of 0.33 uM. |
| PC-26120 |
AFP464
HIF-1α inhibitor, AhR ligand
|
AFP464 (NSC710464) is a prodrug form of Aminoflavone and a small molecule aryl hydrocarbon receptor (AhR) ligand, inhibits HIF-1alpha expression in an AhR-independent fashion (IC50=0.25 uM). |
| PC-26119 |
Aminoflavone
AhR ligand
|
Aminoflavone is a small molecule aryl hydrocarbon receptor (AhR) ligand, inhibits HIF-1alpha expression in an AhR-independent fashion, also inhibits α6-integrin expression and breast cancer sphere-initiating capacity. |
| PC-26117 |
ZSTK3744 hydrochloride
AhR agonist
|
ZSTK3744 hydrochloride is a small molecule Aryl hydrocarbon receptor (AhR) agonist, exhibits cell growth inhibitory activity with IC50 of 0.87 nM for chemotherapy-resistant TNBC MDA-MB-468 cells. |
| PC-26116 |
ZSTK3744
AhR agonist
|
ZSTK3744 is a small molecule Aryl hydrocarbon receptor (AhR) agonist, exhibits cell growth inhibitory activity with IC50 of 0.87 nM for chemotherapy-resistant TNBC MDA-MB-468 cells. |
| PC-23914 |
Indirubin
AHR ligand
|
Indirubin (Couroupitine B) is a bis-indole alkaloid and has emarkable anticancer activity against CML, is a high affinity ligand of aryl hydrocarbon receptor (AHR) with dissociation constant (KD) value of 46.6 nM. |
| PC-23605 |
BAY-218
AhR inhibitor
|
BAY-218 is a specific aryl hydrocarbon receptor (AHR) antagonist, inhibits AHR with IC50 of 39.9 nM in in U87 glioblastoma cells. |
