| Cat. No. |
Product Name |
Information |
| PC-62063 |
VU 0463271
KCC2 inhibitor
|
VU 0463271 is a potent, selecitve inhibitor of the neuronal K-Cl cotransporter KCC2 with IC50 of 61 nM. |
| PC-60024 |
CLP257
KCC2 activator
|
CLP257 (CLP-257) is a potent, selective K+-Cl- cotransporter KCC2 activator with EC50 of 616 nM. |
| PC-47506 |
Chlorotoxin
Chloride channel inhibitor
|
Chlorotoxin is a 36-amino acid peptide found in the venom of the deathstalker scorpion (Leiurus quinquestriatus). |
| PC-22008 |
NMD670 sodium
ClC-1 inhibitor
|
NMD670 (NMD-670) sodium salt is a potent, specific and orally bioavailable ClC-1 chloride channel inhibitor with EC50 of 1.6 uM, restores muscle function in rat models of myasthenia gravis (MG). |
| PC-22007 |
NMD670
ClC-1 inhibitor
|
NMD670 (NMD-670) is a potent, specific and orally bioavailable ClC-1 chloride channel inhibitor with EC50 of 1.6 uM, restores muscle function in rat models of myasthenia gravis (MG). |
| PC-21203 |
OV350
KCC2 activator
|
OV350 (OV-350) is a potent, selective and direct K+-Cl- cotransporter KCC2 agonist with EC50 of 261.4 nM, with no effect on KCC2 plasma membrane accumulation and phosphorylation. |
| PC-20363 |
CaCCinh-A01
CaCC inhibitor
|
CaCCinh-A01 is a small molecule Ca(2+)-activated Cl(-) channel (CaCC) inhibitor, inhibits both I(sc) and transepithelial conductance in a concentration-dependent manner (IC50=6.3 uM). |
| PC-72552 |
CLC-2-IN-AK42
CLC-2 inhibitor
|
CLC-2-IN-AK42 (CLC-2 inhibitor AK42, AK42) is a potent, specific small-molecule inhibitor of voltage-gated chloride channel CLC-2 with IC50 of 17 nM (human CLC-2). |
