| Cat. No. |
Product Name |
Information |
| PC-35775 |
CLP290
KCC2 activator
|
CLP290 (CLP-290) is an orally acirtve small molecule K+-Cl- cotransporter isotype 2 (KCC2) activator, the carbamate prodrug of CLP257. |
| PC-35541 |
DRAinh-A250
SLC26A3 inhibitor
|
DRAinh-A250 is a specific inhibitor of Cl-/anion exchanger SLC26A3 (DRA), fully and reversibly inhibits SLC26A3-mediated Cl- exchange with HCO3-, I-, and thiocyanate (SCN-) with IC50 of ~0.2 uM. |
| PC-43155 |
IAA-94
Chloride channel inhibitor
|
IAA-94 is an indanyloxyacetic acid (IAA) inhibitor of epithelial chloride channels that binds channels in bovine kidney cortex microsomes with Ki of 1 uM. |
| PC-62452 |
OADS
CLC Channel inhibitor
|
OADS is a specific, reversible, small-molecule inhibitor directs against CLC (Chloride Channel) antiporter with Ki of 29 uM, has no specific effect on a CLC channel (ClC-1). . |
| PC-62063 |
VU 0463271
KCC2 inhibitor
|
VU 0463271 is a potent, selecitve inhibitor of the neuronal K-Cl cotransporter KCC2 with IC50 of 61 nM. |
| PC-60024 |
CLP257
KCC2 activator
|
CLP257 (CLP-257) is a potent, selective K+-Cl- cotransporter KCC2 activator with EC50 of 616 nM. |
| PC-47506 |
Chlorotoxin
Chloride channel inhibitor
|
Chlorotoxin is a 36-amino acid peptide found in the venom of the deathstalker scorpion (Leiurus quinquestriatus). |
| PC-22008 |
NMD670 sodium
ClC-1 inhibitor
|
NMD670 (NMD-670) sodium salt is a potent, specific and orally bioavailable ClC-1 chloride channel inhibitor with EC50 of 1.6 uM, restores muscle function in rat models of myasthenia gravis (MG). |
| PC-22007 |
NMD670
ClC-1 inhibitor
|
NMD670 (NMD-670) is a potent, specific and orally bioavailable ClC-1 chloride channel inhibitor with EC50 of 1.6 uM, restores muscle function in rat models of myasthenia gravis (MG). |
