| Cat. No. |
Product Name |
Information |
| PC-24926 |
Opa1 inhibitor 0
Opa1 inhibitor
|
Opa1 inhibitor 0 (Opitor-0) is a reversible, noncompetitive inhibitor of mitochondrial dynamin-related protein Optic Atrophy 1 (OPA1) with IC50 of 3.0 uM against GTPase activity, effectively induces mitochondrial fragmentation in both human and mouse cells. |
| PC-21364 |
Mdivi-1
Drp1 inhibitor
|
Mdivi-1 (Mitochondrial division inhibitor 1) is a selective dynamin-related protein 1 (Drp1) inhibitor and mitochondrial division/mitophagy inhibitor. |
| PC-20783 |
Dyngo-4a
Dynamin inhibitor
|
Dyngo-4a (Hydroxy Dynasore) is a potent Dynasore analog and dynamin inhibitor with IC50 of 0.38 and 2.6 uM for dynamin I and dynamin II, respectively, inhibits endocytosis. |
| PC-20700 |
Dynasore
Dynamin inhibitor
|
Dynasore is a specific, cell-permeable inhibitor of dynamin GTPase function, acts as a potent inhibitor of endocytic pathways known to depend on dynamin by rapidly blocking coated vesicle formation. |
| PC-49583 |
DRP1i27
Drp1 inhibitor
|
DRP1i27 is a novel inhibitor of human Drp1 (mitochondrial dynamin-related protein 1), directly binds to and inhibits GTPase activity of human Drp1. |
| PC-38609 |
MYLS22
Opa1 inhibitor
|
MYLS22 is a specific, nontoxic small molecule inhibitor of the inner mitochondrial membrane mitochondrial fusion protein optic atrophy 1 (OPA1), curtails tumor growth and metastasisin vitro and in vivo. |
| PC-35265 |
DRP1 inhibitor 4
Drp1 inhibitor
|
DRP1 inhibitor 4 is a selective, small molecule inhibitor of the mammalian mitochondrial division dynamin, DRP1 with IC50 of 1.0 uM, shows no activity against OPA1 and DYN1 (IC50>100 uM).. |
| PC-63280 |
Bis-T-23
Dynamin modulator
|
Bis-T-23 is a small molecule that stimulates actin-dependent dynamin oligomerization and promotes dynamin GTPase activity, increases actin polymerization in injured podocytes. |
| PC-63240 |
Dynole 34-2
Dynamin GTPase inhibitor
|
Dynole 34-2 is a potent dynamin GTPase inhibitor with IC50 of 6.9 and 14.2 uM for full-length dynI and dynII GTPase activity, respectively. |
| PC-62371 |
Pyrimidyn 7
Dynamin inhibitor
|
Pyrimidyn 7 is a potent, dual-action dynamin GTPase activity inhibitor with IC50 of 1.1 uM/1.8 uM for dynamin I/dynamin II respectively, competitively inhibits both GTP and phospholipid interactions with dynamin. |
| PC-24289 |
Drp1 inhibitor P110
Drp1 inhibitor
|
Drp1 inhibitor P110 (Compound P110) is a selective Drp1 peptide inhibitor with neuroprotective properties, inhibits the activation of Drp1, prevent MPTP-induced Drp1 mitochondrial translocation. |
| PC-20940 |
Drp1 inhibitor SC9
Drp1 inhibitor
|
Drp1 inhibitor SC9 (Drp1 SWAG ligand SC9) is a small molecule binder of dynamin-related protein 1 (Drp1) allosteric site switch I-adjacent groove (SWAG), inhibits GTPase activity of Drp1 (IC50=270 nM) and inhibits Drp1-Fis1 interaction in cells. |
