| Cat. No. |
Product Name |
Information |
| PC-24796 |
CATPB
FFA2 antagonist
|
CATPB is a potent, selective free fatty acid receptor 2 (FFA2R, GPR43) antagonist with cAMP pIC50 of 6.96 and GTPγS pIC50 of 6.68, shows inverse agonist properties. |
| PC-24795 |
GPR43 agonist compound 187
GPR43 agonist
|
GPR43 agonist compound 187 is a potent, selective GPR43 (FFAR2 or FFA2) agonist, induces Rho GTPase signaling to activate YAP/TAZ, causes YAP/TAZ accumulated in the nucleus in GPR43-expressing HEK293 cells in a manner dependent on Gα12/13 and Gαq/11. |
| PC-24589 |
DFL23916
GPR40/GPR120 agonist
|
DFL23916 is a new selective, dual GPR40 and GPR120 agonist with AC50 of 16.6 µM on human GPR120 short isoform and AC50 of 13.7 µM on human GPR40. |
| PC-24516 |
ZYDG2 calcium salt
GPR40 agonist
|
ZYDG2 hemicalcium salt is a potent and selective agonist for GPR40 (FFAR1) with EC50 of 41 nM and 17 nM in cell-based functional inositol 1-phosphate-ELISA assay and Ca2+ mobilization assay, respectively. |
| PC-24515 |
ZYDG2
GPR40 agonist
|
ZYDG2 is a potent and selective agonist for GPR40 (FFAR1) with EC50 of 41 nM and 17 nM in cell-based functional inositol 1-phosphate-ELISA assay and Ca2+ mobilization assay, respectively. |
| PC-24334 |
4-CMTB
FFA2 agonist
|
4-CMTB is a selective, allosteric free fatty acid receptor 2 (FFA2, GPR43) agonist and positive allosteric modulator (pEC50=6.38). |
| PC-20869 |
GPR40 agonist AP4
GPR40 agonist
|
GPR40 agonist AP4 is a potent, selective, full allosteric agonist (AgoPAM) of GPR40 with EC50 of 0.08 nM, Emax=283%. |
