| Cat. No. |
Product Name |
Information |
| PC-20424 |
Metabolex-36
GPR120 (FFAR4) agonist
|
Metabolex-36 is a potent, selective GPR120 (FFAR4) agonist with EC50 of 570 nM and 130 nM for stimulation of DMR response in CHO-hGPR120/mGPR120 cells, respectively. |
| PC-20423 |
AZ13595491
GPR120 (FFAR4) agonist
|
AZ13595491 (AZ491) is a potent, selective G-protein-coupled receptor GPR120 (FFAR4) agonist with IC50 of 0.74/1.0 uM for huamn/mouse GPR120, respectively. |
| PC-20422 |
AZ423
GPR120 (FFAR4) agonist
|
AZ423 (AZ13595423, AZ-423) is a potent, selective G-protein-coupled receptor GPR120 (FFAR4) agonist with IC50 of 0.36/0.51 uM for huamn/mouse GPR120, respectively. |
| PC-20421 |
TUG-424
GPR40 agonist
|
TUG-424 (TUG424) is a potent, selective free fatty acid receptor 1 (FFA1, GPR40) agonist with EC50 of 32 nM, TUG-424 (100 nM) enhances glucose-stimulated insulin secretion from rat INS-1E cells and isolated mouse islets. |
| PC-49032 |
AR420626
GPR41 agonist
|
AR420626 is a potent, selective GPR41/FFA3 agonist with pEC50 of 5.74 in [35S]GTPγS-binding assays, induces apoptosis in HCC cells, including HepG2 and HLE cells. |
| PC-72422 |
CFMB
FFAR2 (GPR43) agonist
|
CFMB (FFA2R agonist 58) is a potent, allosteric FFAR2 (GPR43) agonist/modulator. |
| PC-72120 |
CPL207280-51
GPR40 agonist
|
CPL207280-51 is a stable, solid form of CPL207280, a potent, selective GPR40/FFA1 agonist (EC50=80 nM). |
| PC-72119 |
CPL207280
GPR40 agonist
|
CPL207280 (CPL 207280) is a novel potent, selective GPR40/FFA1 agonist with EC50 of 80 nM in a Ca2+ influx assay, shows greater potency than fasiglifam (EC50=270 nM). |
| PC-72109 |
SCO-267
GPR40 agonist
|
SCO-267 (SCO267) is a potent, orally available GPR40/FFAR1 full agonist with EC50 of 12 nM (hGPR40). |
| PC-38228 |
MK-8666
GPR40 agonist
|
MK-8666 is a potent, selective partial GPR40 agonist with EC50 of 0.9 nM, shows potential for the treatment of type 2 diabetes mellitus. |
| PC-35696 |
(S)-4CMTB
FFA2 agonist
|
(S)-4CMTB (S-4CMTB, AMG 7703, Phenylacetamide 1) is a potent, specific and allosteric agonist of FFA2 (GPR43) with cAMP IC50 of 0.7 and 0.96 uM for hFFA2 and mFFA2, respectively. |
| PC-35695 |
TUG-1375
FFA2/GPR43 agonist
|
TUG-1375 (TUG1375, TUG 1375) is a potent, selective free fatty acid receptor 2 (FFA2/GPR43) agonist with β-arrestin-2 pEC50 of 6.1 and cAMP pEC50 of 7.11. |
