You are here:Home-Chemical Inhibitors & Agonists-Membrane Transporter/Ion Channel-Glutamate Transporter

Request The Product List ofGlutamate Transporter Glutamate Transporter

Cat. No. Product Name Information
PC-36103

Trigriluzole

Trigriluzole (BHV-4157) is a novel glutamate modulator for the treatment of mild-to-moderate Alzheimer’s disease (AD).
PC-62149

UCPH-102

UCPH-102 is a selective, brain penetrant inhibitor of EAAT1 (Excitatory amino acid transporter 1) with IC50 of 420 nM.
PC-62148

UCPH-101

UCPH-101 is a selective non-substrate inhibitor of EAAT1 (Excitatory amino acid transporter 1) with IC50 of 660 nM.
PC-61675

LDN 0212320

LDN0212320 (OSU 0212320) is a small-molecule activator of glutamate transporter EAAT2 translation with EC50 of 1.83 uM.
PC-50008

V-9302

ASCT2 inhibitor

V-9302 (V9302) is a competitive, selective antagonist of transmembrane glutamine flux that selectively and potently targets the amino acid transporter ASCT2 with IC50 of 9.6 uM.
PC-61185

L-g-glutamyl-p-nitroanilide hydrochloride

L-g-glutamyl-p-nitroanilide hydrochloride is a potent, competitive inhibitor of the neutral amino acid transporter ASCT2 (SLC1A5) with pKa of 13.79.
PC-20248

NV-6297

GLUT-1 inhibitor

NV-6297 (NV6297) is a potent, selective mTORC1 pathway signaling inhibitor without inhibition on mTORC2, inhibits S6K1 phosphorylation (pS6K1 T389) in MCF7 cells with IC50 of 120 nM, directly and selectively targets GLUT-1.
PC-20247

NV-5440

GLUT-1 inhibitor

NV-5440 (NV5440) is a potent, selective mTORC1 pathway signaling inhibitor without inhibition on mTORC2, inhibits S6K1 phosphorylation (pS6K1 T389) in MCF7 cells with IC50 of 70 nM, directly targets GLUT-1 with Ki of 69.3 nM.
PC-49856

GTS467

EAAT2 activator

GTS476 (GTS-476) is a potent, selective, orally active activator of EAAT2 with EC50 of 35.1 nM in vitro glutamate uptake assays in COS cells overexpressing EAAT2.
PC-49855

GT949

EAAT2 activator

GT949 (GT-949) is a potent, selective activator (positive allosteric modulator) of EAAT2 with EC50 of 0.26 nM in vitro glutamate uptake assays in COS cells overexpressing EAAT2.
PC-49854

GTS511

EAAT2 activator

GTS511 (GTS-511) is a potent, selective, brain-permeable activator of EAAT2 with EC50 of 3.8 nM in vitro glutamate uptake assays in COS cells overexpressing EAAT2.
PC-49853

GT951

EAAT2 activator

GT951 (GT-951) is a potent, selective activator (positive allosteric modulator) of EAAT2 with EC50 of 0.8 nM in vitro glutamate uptake assays in COS cells overexpressing EAAT2.

Request The Product List

* Indicates a Required FieldYour information is safe with us.

  • *Product List:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Country:
  • Additional Information:

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com