| Cat. No. |
Product Name |
Information |
| PC-63116 |
IKK2-IN-9
IKK2 inhibitor
|
IKK2-IN-9 is a potent, selective and orally active IKK2 inhibitor with IC50 of 19 nM, displays 20-fold selectivity over IKK1 (IC50=420 nM). |
| PC-63015 |
TBK1-IKKε inhibitor II
TBK1/IKKε inhibitor
|
TBK1-IKKε inhibitor II is a potent, selective dual inhibitor of TBK1/IKKε with IC50 of 13 nM/59 nM, respectively. |
| PC-61282 |
AS602868
IKK2 inhibitor
|
AS602868 (SPC-839) is a potent, selective and ATP-competitive inhibitor of IKK2 with IC50 of 60 nM and Ki of 20 nM, also interfers directly with FLT3 kinase activation. |
| PC-61094 |
PHA-408
IKK2 inhibitor
|
PHA-408 (PHA-767408) is a potent, highly selective, ATP-competitive IKK-2 inhibitor with IC50 of 40 nM, 350-fold selectivity over IKK-1. |
| PC-61066 |
SU-909
IKKα inhibitor
|
SU-909 (SU909, IKKα-IN-48) is a potent, selective IKKα inhibitor with Ki of 0.08±0.07 uM, 10-20-fold selectivity over IKKβ (IC50=1.0±0.28 uM). |
| PC-60552 |
iNUB
NEMO inhibitor
|
iNUB (Inhibitor of NEMO-Ub binding) is a small molecule inhibitor of NEMO (IKKγ)-ubiquitin binding with EC50 of 9.3 uM, directly binds to NEMO with Kd of 2.14 uM. |
| PC-45398 |
PS-1145
IKK inhibitor
|
PS-1145 (PS1145) is a specific IκB kinase (IKK) inhibitor with IC50 of 88 nM. |
| PC-43044 |
WS3
β cells proliferation inducer
|
WS3 is a small molecule that can induce proliferation of β cells with EC50 of 74 nM, modulates the activity of Erb3 binding protein-1 and the IκB kinase pathway. |
| PC-43043 |
WS6
PA2G4 inhibitor
|
WS6 is a small molecule that can induce proliferation of β cells with EC50 of 0.28 uM, also is a selective proliferation-associated 2G4 (PA2G4) inhibitor, interferes with PA2G4-MYCN binding. |
| PC-45916 |
Bay 65-1942
IKKβ inhibitor
|
Bay 65-1942 (BAY651942) is a potent, selective, ATP-competitive inhibitor of IKKβ kinase with Ki of 2 nM. |
| PC-45915 |
Bay 65-1942 hydrochloride
IKKβ inhibitor
|
Bay 65-1942 hydrochloride is a potent, selective, ATP-competitive inhibitor of IKKβ kinase with Ki of 2 nM. |
| PC-42418 |
IMD-0354
IKKβ inhibitor, AQP4 inhibitor
|
IMD-0354 (AER-270) is a potent IκB kinase β (IKKbeta) inhibitor, also is a potent inhibitor of glutamine uptake. |
