| Cat. No. |
Product Name |
Information |
| PC-20488 |
AKU-005
FAAH/MAGL inhibitor
|
AKU-005 is a potent, dual MAGL/FAAH inhibitor with IC50 of 589 and 309 pM for MAGL in rat and mouse brain membrane respectively, inhibits rat and human FAAH with IC50 of 63 and 389 nM. |
| PC-20487 |
JZL195
Dual MAGL/FAAH inhibitor
|
JZL195 (JZL 195) is a potent, selective dual fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL) inhibitor with IC50s of 2 and 4 nM, respectively. |
| PC-20486 |
JZL184
MAGL inhibitor
|
JZL184 (JZL 184) is a potent, selective and irreversible MAGL inhibitor, blocks 2-Arachidonoylglycerol (2-AG) hydrolysis in brain membranes with IC50 of 8 nM, >300-fold selectivity for MAGL over FAAH. |
| PC-49167 |
MAGLi 432
MAGL inhibitor
|
MAGLi 432 is a highly selective, potent and reversible monoacylglycerol lipase (MAGL) inhibitor with IC50 of 4.2 and 3.1 nM for human and mouse MAGL enzyme, respectively. |
| PC-73016 |
AM6580
MAGL covalent inhibitor
|
AM6580 is a potent, covalent monoacylglycerol lipase (MAGL) inhibitor with IC50 of 3 nM (hMAGL). |
| PC-73012 |
AM9928
MAGL covalent inhibitor
|
AM9928 is a potent, covalent monoacylglycerol lipase (MAGL) inhibitor with IC50 of 8.9 nM (hMAGL). |
| PC-72112 |
JNJ-42226314
MAGL inhibitor
|
JNJ-42226314 (JNJ42226314) is a potent, highly selective and reversible MAGL inhibitor with IC50 of 1.13 nM (hMAGL). |
| PC-35522 |
ABX-1431
MAGL inhibitor
|
Elcubragistat (ABX1431) is a highly potent, selective, orally available, CNS-penetrant monoacylglycerol lipase (MAGL) with IC50 of 14 nM (hMAGL). |
| PC-63525 |
PF-06795071
MAGL inhibitor
|
PF-06795071 is a potent, selective, covalent Monoacylglycerol Lipase (MAGL) inhibitor with IC50 of 3 nM, >1,000-fold selectivity over FAAH. |
| PC-42980 |
JW 642
MAGL inhibitor
|
JW 642 (JW642) is a potent, selective monoacylglycerol lipase (MAGL) inhibitor with IC50 of 7.6, 14 and 3.7 nM for mouse, rat and human MAGL, respectively. |
| PC-60707 |
MJN110
MAGL inhibitor
|
MJN110 (MJN-110) is a potent, selective, and orally active MAGL inhibitor with IC50 of 2.1 nM (2-AG hydrolysis). |
| PC-60701 |
JJKK-048
MAGL inhibitor
|
JJKK-048 (JJKK048) is a potent, highly selective monoacylglycerol lipase (MAGL) with IC50 of <0.4 nM against human and rodent MAGL. |
