| Cat. No. |
Product Name |
Information |
| PC-60410 |
APX-115
NADPH oxidase inhibitor
|
Isuzinaxib (APX-115, Ewha 18278) is a first-in-class, orally active, pan-NADPH oxidase (Nox) inhibitor with Ki of 1.08, 0.57, 0.63 nM for Nox1, Nox2, and Nox4, respectively. |
| PC-60409 |
APX-115 freebase
NADPH oxidase inhibitor
|
Isuzinaxib (APX-115, Ewha 18278) is a first-in-class, orally active, pan-NADPH oxidase (Nox) inhibitor with Ki of 1.08, 0.57, 0.63 nM for Nox1, Nox2, and Nox4, respectively. |
| PC-45569 |
GSK-2795039
NOX2 inhibitor
|
GSK-2795039 (GSK2795039) is a potent and selective inhibitor of NOX2 (NADPH oxidase 2) with pIC50 of 6.57. |
| PC-22018 |
GKT136901
NOX1/4 inhibitor
|
GKT136901 is a potent, selective and orally active inhibitor of NADPH oxidase NOX1/4 with Ki values of 160 and 165 nM, respectively. |
| PC-49686 |
NCATS-SM7270
NOX2 inhibitor
|
NCATS-SM7270 is a specific small molecule NADPH oxidase 2 (NOX2) inhibitor with IC50 of 2.1 uM (Polymorphonuclear leukocytes, PMN), inhibits NOX2 in primary human and mouse granulocytes. |
| PC-73001 |
GLX7013114
Nox4 inhibitor
|
GLX7013114 (GLX-7013114) is a novel selective NADPH oxidase 4 (Nox4) inhibitor with IC50 of 0.3 uM in in CJ Nox4 HEK 293 cell asays. |
