| Cat. No. |
Product Name |
Information |
| PC-42185 |
Aprepitant
NK-1 receptor inhibitor
|
Aprepitant (MK-0869) is a potent, orally active, long-acting human NK-1 receptor (substance P receptor) antagonist with IC50 of 0.09 nM. |
| PC-22655 |
SR140333B
NK1 receptor antagonist
|
Nolpitantium besilate (SR140333B) is a potent, selective, non-peptide NK1 receptor antagonist with Ki of 0.74 nM, IC50 of 1.6 nM. |
| PC-21757 |
Elinzanetant
NK1/3R inhibitor
|
Elizanetant (NT-814) is an orally active, selective neurokinin (NK) receptors 1 and 3 antagonist, modulates reproductive hormone secretion. |
| PC-38599 |
Tradipitant
NK1R antagonist
|
Tradipitant (VLY-686, LY686017) is a selective, orally bioavailable, centrally-acting neurokinin-1 receptor (NK1) antagonist with potential anti-emetic, anti-pruritic and anti-inflammatory activities. |
| PC-62979 |
Maropitant citrate
|
Maropitant citrate (Cerenia) is a selective neurokinin 1 receptor (NK1) antagonist for prevention of vomiting due to motion sickness in dogs.. |
| PC-62976 |
GR-73632
|
GR-73632 is a potent and selective tachykinin NK1 receptor agonist with EC50 of 2 nM, promotes differentiation but not survival of rat chromaffin cells in vitro.. |
| PC-61579 |
Vestipitant mesylate
|
Vestipitant (GW597599) is a potent, selective, orally active NK1 receptor antagonist with pKi of 9.65. |
| PC-61552 |
Orvepitant
|
Orvepitant (GW823296) is a potent and selective, brain penetrant NK1 receptor antagonist with pKi of 10.2. |
| PC-60341 |
L-732138
|
A potent, selective and competitive NK1 receptor antagonist with IC50 of 2.3 nM. |
| PC-70194 |
L-733060 hydrochloride
|
An orally active, non-peptide, selective antagonist for the NK1 receptor with Ki of 0.8 nM. |
| PC-70193 |
L-733060
|
An orally active, non-peptide, selective antagonist for the NK1 receptor with Ki of 0.8 nM. |
| PC-70192 |
GR-159897
|
A potent non-peptide antagonist of tachykinin NK2 receptor with pKi of 9.5 in CHO cells. |
