| Cat. No. |
Product Name |
Information |
| PC-61578 |
Vestipitant
NK1R antagonist
|
Vestipitant (GW597599) is a potent, selective, orally active NK1 receptor antagonist with pKi of 9.65. |
| PC-61552 |
Orvepitant
NK1 receptor antagonist
|
Orvepitant (GW823296) is a potent and selective, brain penetrant NK1 receptor antagonist with pKi of 10.2. |
| PC-61237 |
MLE4901
NK3R antagonist
|
Pavinetant (MLE4901, AZD-2624) is a potent, selective, orally active neurokinin 3 (NK3R) antagonist for the treatment of menopausal hot flushes. |
| PC-60342 |
SR140333
NK1 receptor antagonist
|
Nolpitantium (SR140333) is a potent, selective, non-peptide NK1 receptor antagonist with Ki of 0.74 nM, IC50 of 1.6 nM. |
| PC-60341 |
L-732138
NK1 receptor antagonist
|
L-732138 is a potent, selective and competitive NK1 receptor antagonist with IC50 of 2.3 nM. |
| PC-70195 |
Fezolinetant
NK3R inhibitor
|
Fezolinetant (ESN-364) is a potent, selective, orally active neurokinin-3 receptor (NK3R) antagonist with pIC50/pKi of 7.7/7.6. |
| PC-70194 |
L-733060 hydrochloride
NK1 receptor antagonist
|
L-733060 hydrochloride is an orally active, non-peptide, selective antagonist for the NK1 receptor with Ki of 0.8 nM. |
| PC-70193 |
L-733060
NK1 receptor antagonist
|
L-733060 is an orally active, non-peptide, selective antagonist for the NK1 receptor with Ki of 0.8 nM. |
| PC-70192 |
GR159897
NK2 receptor antagonist
|
GR159897 is a potent non-peptide antagonist of tachykinin NK2 receptor with pKi of 9.5 in CHO cells. |
| PC-70191 |
Ibodutant
NK2 receptor antagonist
|
Ibodutant (MEN-15596) is a potent and selective linear tachykinin NK2 receptor antagonist with pKb of 9.3. |
| PC-70190 |
RP-67580
NK1 receptor antagonist
|
RP-67580 is a potent and selective tachykinin NK1 receptor antagonist with Ki of 2.9 nM. |
| PC-70189 |
Saredutant
NK2 receptor antagonist
|
Saredutant (SR48968) is a potent and selective non-peptide antagonist of the neurokinin A (NK2) receptor. |
