| Cat. No. |
Product Name |
Information |
| PC-70193 |
L-733060
NK1 receptor antagonist
|
L-733060 is an orally active, non-peptide, selective antagonist for the NK1 receptor with Ki of 0.8 nM. |
| PC-70192 |
GR159897
NK2 receptor antagonist
|
GR159897 is a potent non-peptide antagonist of tachykinin NK2 receptor with pKi of 9.5 in CHO cells. |
| PC-70191 |
Ibodutant
NK2 receptor antagonist
|
Ibodutant (MEN-15596) is a potent and selective linear tachykinin NK2 receptor (NK2R) antagonist with pKb of 9.3. |
| PC-70190 |
RP-67580
NK1 receptor antagonist
|
RP-67580 is a potent and selective tachykinin NK1 receptor antagonist with Ki of 2.9 nM. |
| PC-70189 |
Saredutant
NK2 receptor antagonist
|
Saredutant (SR48968) is a potent and selective non-peptide antagonist of the neurokinin A (NK2) receptor. |
| PC-60173 |
NK1-IN-9
NK1/SERT inhibitor
|
NK1-IN-9 is a potent, orally active, dual NK1 receptor antagonist (IC50=0.5 nM) and SERT inhibitor (IC50=5.2 nM). |
| PC-42191 |
Maropitant
NK1 receptor antagonist
|
Maropitant (CJ-11972) is a selective neurokinin 1 receptor (NK1) antagonist for prevention of vomiting due to motion sickness in dogs. |
| PC-42185 |
Aprepitant
NK-1 receptor antagonist
|
Aprepitant (MK-0869) is a potent, orally active, long-acting human NK-1 receptor (substance P receptor) antagonist with IC50 of 0.09 nM. |
| PC-45396 |
NKP608
NK1 receptor antagonist
|
NKP608 (NKP-608) is a non-peptidic, specific, potent and orally active NK1 receptor antagonist with IC50 of 2.6 nM. |
| PC-44659 |
SB222200
NK3 receptor antagonist
|
SB-222200 (SB222200) is a CNS-penetrant, potent and selective NK-3 receptor antagonist with Ki of 4.4 nM (inhibition of neurokinin B binding to CHO-hNK-3R). |
| PC-27468 |
Grexenetant
NK3R antagonist
|
Grexenetant is a potent, selective neurokinin 3 receptor (NK3R) antagonist. |
| PC-27027 |
Netupitant
NK1R antagonist
|
Netupitant (CID 6451149) is a highly potent, selective and orally active neurokinin-1 receptor (NK1R) antagonist with Ki of 0.95 nM for hNK1 receptor, >1000-fold selective over NK2R and NK3R. |
