| Cat. No. |
Product Name |
Information |
| PC-20648 |
AZD1283
P2Y12 antagonist
|
AZD1283 (AZD-1283) is a potent, selective P2Y12 receptor antagonist with binding IC50 of 11 nM, and IC50 of 3.2 uM in washed platelet assay (WPA). |
| PC-49620 |
MRS4853
P2Y6 inhibitor
|
MRS4853 is a selective P2Y6 receptor (P2Y6R) antagonist with IC50 of 0.46 uM (hP2Y6R), displays weak affinity for mP2Y6R (IC50=6.15 uM). |
| PC-35578 |
ACT-281959
P2Y12 inhibitor
|
ACT-281959 (ACT281959) is the prodrug of ACT-246475, which is a potent, selective, reversible P2Y12 receptor antagonist with binding IC50 of 1.0 nM. |
| PC-35577 |
ACT-246475
P2Y12 antagonist
|
ACT-246475 (ACT246475) is a potent, selective, reversible P2Y12 receptor antagonist with binding IC50 of 1.0 nM. |
| PC-35051 |
PPTN trifluoroacetate salt
P2Y14 antagonist
|
PPTN is a potent, highly specific antagonist of P2Y14 receptor with Ki of 0.4 nM in functional assays. |
| PC-35050 |
PPTN
P2Y14 antagonist
|
PPTN is a potent, highly specific antagonist of P2Y14 receptor with Ki of 0.4 nM in functional assays. |
| PC-35049 |
MRS4478
P2Y14 antagonist
|
MRS4478 is a potent, highly specific antagonist of P2Y14 receptor with IC50 of 269 nM, does not display extensive off-target interactions with biogenic amine receptors. |
| PC-35048 |
MRS4458
P2Y14 antagonist
|
MRS4458 is a potent, highly specific antagonist of P2Y14 receptor with IC50 of 169 nM, does not display extensive off-target interactions with biogenic amine receptors. |
| PC-63561 |
BMS-884775
P2Y1 antagonist
|
BMS-884775 is a potent, selective P2Y1 antagonist with IC50 of 0.12 nM. |
| PC-43381 |
MRS2578
P2Y6 antagonist
|
MRS2578 is a potent, selective P2Y6 receptor antagonist with IC50 of 37 nM (human) and 101 nM (rat). |
| PC-62046 |
YM-254890
Gq signaling inhibitor
|
YM 254890 is a selective Gq signaling inhibitor that strongly inhibits intracellular calcium ion mobilization and serum response element (SRE)-mediated transcription stimulated by several receptors coupled to Gq, but not those coupled to Gi, Gs, or G15. |
| PC-61744 |
MRS2179 tetrasodium
P2Y1 antagonist
|
MRS 2179 is a potent, selective, competitive P2Y1 receptor antagonist with Kb of 100 nM. |
