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Cat. No. Product Name Information
PC-49753

PARP-1 inhibitor Pip6

PARP1 inhibitor

PARP-1 inhibitor Pip6 is an analog of PARP-1 type I inhibitor AZ0108, shows similar type I inhibition of PARP-1 but is 90-fold more cytotoxic than AZ0108.
PC-49585

KMR-206

PARP7 inhibitor

KMR-206 (KMR206) is a potent, selective PARP7 inhibitor with IC50 of 13.7 nM, displays 75-fold selectivity for PARP7 over PARP2 and does not inhibit PARP1 up to 3 uM.
PC-49520

RBN-012759

PARP14 inhibitor

RBN-012759 (RBN012759) is a potent and highly selective PARP14 chemical probe inhibitor with biochemical IC50 of 3 nM in TR-FRET assays, >300-fold selectivity over all PARP family members.
PC-72899

AZD9574

PARP1 inhibitor

AZD9574 (AZD-9574) is a potent, selective and CNS penetrant PARP1 inhibitor, inhibits PARP1 enzymatic activity with IC50 of 0.3-2.0 nM in a panel of cell lines irrespective of the HRR status.
PC-49120

STP1002

TNKS1/2 inhibitor

STP1002 (Basroparib) is a potent, selective and orally active inhibitor of tankyrase 1/2 (TNKS1/2) with IC50 of 5.8/3.2 nM, respectively, shows excellent selectivity against PARP1/2 compared to XAV939.
PC-72966

COH34

PARG inhibitor

COH34 (PARG inhibitor COH34, NSC191252) is a potent, selective and cell-active PARG inhibitor (IC50=0.37 nM).
PC-72910

PARPYnD

PARP photoaffinity probe

PARPYnD is the first cell-active photoaffinity probe (AfBP) for PARP protein class, based on triple PARP1/2/6 inhibitor AZ9482.
PC-72698

AEP07

PARP4 inhibitor

AEP07 (AEP 07) is a selective small molecule inhibitor of PARP4 (vPARP) inhibitor with IC50 of 0.8 uM, >12-fold selective over other PARP family members.
PC-72334

RBN-2397

PARP7 inhibitor

RBN-2397 (Atamparib, RBN2397) is a potent, selective, orally active NAD+ competitive inhibitor of PARP7 with IC50 of <3 nM and Kd of <1 nM.
PC-72149

AMXI-5001

PARP inhibitor

AMXI-5001 (AMXI 5001) is a novel, highly potent, orally active dual PARP1/2 (IC50 5/0.05 nM) and microtubule polymerization inhibitor, inhibits intracellular PAR formation with IC50 of 7 nM.
PC-38102

Venadaparib

PARP inhibitor

Venadaparib (IDX-1197) is a potent, selective PARP inhibitor with IC50 of 1.4 nM and 1.0 nM for PARP1 and PARP2, respectively.
PC-38045

DR2313

PARP inhibitor

DR2313 is a PARP inhibitor, inhibits poly(ADP-ribosyl)ation in nuclear extracts of rat brain in vitro (Ki=0.23 uM).

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