| Cat. No. |
Product Name |
Information |
| PC-72698 |
AEP07
PARP4 inhibitor
|
AEP07 (AEP 07) is a selective small molecule inhibitor of PARP4 (vPARP) inhibitor with IC50 of 0.8 uM, >12-fold selective over other PARP family members. |
| PC-72405 |
AZD5305
PARP1 inhibitor
|
Saruparib (AZD5305) is a potent, selective, orally active PARP1 inhibitor (IC50=3 nM) and PARP1-DNA trapper. |
| PC-72334 |
RBN-2397
PARP7 inhibitor
|
RBN-2397 (Atamparib, RBN2397) is a potent, selective, orally active NAD+ competitive inhibitor of PARP7 with IC50 of <3 nM and Kd of <1 nM. |
| PC-72312 |
RP12146
PARP1/2 inhibitor
|
RP12146 (RP12146) is a novel, selective, and potent small molecule inhibitor of PARP1/2 with IC50 of 0.6/0.5 nM, with several fold selectivity over other isoforms. |
| PC-72150 |
AMXI-5001 hydrochloride
PARP inhibitor
|
AMXI-5001 hydrochloride (AMXI 5001) is a novel, highly potent, orally active dual PARP1/2 (IC50 5/0.05 nM) and microtubule polymerization inhibitor, inhibits intracellular PAR formation with IC50 of 7 nM. |
| PC-72149 |
AMXI-5001
PARP inhibitor
|
AMXI-5001 (AMXI 5001) is a novel, highly potent, orally active dual PARP1/2 (IC50 5/0.05 nM) and microtubule polymerization inhibitor, inhibits intracellular PAR formation with IC50 of 7 nM. |
| PC-38102 |
Venadaparib
PARP inhibitor
|
Venadaparib (IDX-1197) is a potent, selective PARP inhibitor with IC50 of 1.4 nM and 1.0 nM for PARP1 and PARP2, respectively. |
| PC-38045 |
DR2313
PARP inhibitor
|
DR2313 is a PARP inhibitor, inhibits poly(ADP-ribosyl)ation in nuclear extracts of rat brain in vitro (Ki=0.23 uM). |
| PC-36037 |
Fluzoparib
PARP inhibitor
|
Fluzoparib (Fuzuloparib, SHR-3162) is a novel, potent and orally available inhibitor of PARP with IC50 of 1.46 nM (PARP1). |
| PC-36012 |
PARP10 inhibitor 22
PARP10 inhibitor
|
PARP10 inhibitor 22 is a selective, cell-active inhibitor of PARP10 with IC50 of 1.8 uM, exhibits >10-fold selectivity over a large subset of other PARP family members. |
| PC-36007 |
MSC2504877
TNKS1/2 inhibitor
|
MSC2504877 (M2912) is a novel small molecule selective tankyrase inhibitor with IC50 of 0.7/0.8 nM against TNKS1/2, shows 771-fold selectivity for TNKS1 over PARP1 (IC50=0.54 uM). |
| PC-35720 |
PARP11 inhibitor ITK7
PARP11 inhibitor
|
PARP11 inhibitor ITK7 (ITK7) is a potent and selective PARP11 inhibitor with IC50 of 14 nM, displays >200-fold selectivity over other PARPs. |
