| Cat. No. |
Product Name |
Information |
| PC-42269 |
BGP-15
PARP inhibitor, Hsp72 modulator
|
BGP-15 is a PARP inhibitor and an inducer of HSF-1/HSP72 (cotreatment with heat) in vtiro, has no effect on HSP90 levels. |
| PC-45086 |
WIKI4
TNKS2 inhibitor, Wnt/β-catenin inhibitor
|
WIKI4 is a novel small molecule inhibitor of the Wnt/β-catenin pathway by inhibiting the enzymatic activity of TNKS2. |
| PC-42683 |
Niraparib tosylate
PARP1/2 inhibitor
|
Niraparib tosylate (MK-4827) is a highly potent PARP inhibitor with IC50 of 3.8 nM/2.1 nM for PARP1/PARP2. |
| PC-42682 |
MK-4827 hydrochloride
PARP1/2 inhibitor
|
Niraparib (MK-4827) hydrochloride is a highly potent PARP inhibitor with IC50 of 3.8 nM/2.1 nM for PARP1/PARP2. |
| PC-42681 |
Niraparib
PARP inhibitor
|
Niraparib (MK-4827, MK4827) is a highly potent PARP inhibitor with IC50 of 3.8 nM/2.1 nM for PARP1/PARP2. |
| PC-42678 |
A-966492
PARP inhibitor
|
A-966492 (A966492) is a highly potent and efficacious PARP inhibitor with Ki/EC50 of 1 nM/1 nM for PARP-1. |
| PC-27584 |
PARP7 inhibitor B-6
PARP7 inhibitor
|
PARP7 inhibitor B-6 is a potent, brain-penetrant PARP7 inhibitor with IC50 of 22.8 nM. |
| PC-26674 |
NU1025
PARP inhibitor
|
NU1025 is a potent PARP inhibitor with IC50 of 400 nM and Ki of 48 nM, potentiates the cytotoxicity of ionizing radiation and anticancer agents, shows anti-cancer and neuroprotective activity. |
| PC-26590 |
XW-17
PARP14 inhibitor
|
XW-17 is a highly potent, selective PARP14 inhibitor with IC50 of 3.03 nM. |
| PC-26517 |
DB008
PARP16 inhibitor
|
DB008 is a selective, covalent PARP16 inhibitor with IC50 of 0.275 uM, covalently reacts with a non-conserved cysteine (Cys169, human numbering) in the NAD+ binding pocket of PARP16. |
| PC-26332 |
Ivuparib
PARP inhibitor
|
Ivuparib is a potent poly (ADP-ribose) polymerase (PARP) inhibitor with antineoplastic activities. |
| PC-25988 |
ARCher-142
TNKS2 ARC4 inhibitor
|
ARCher-142 (S8/ARCher-142) is a specific TNKS2 ARC4 inhibitor that specifically targeting the ARC4 peptide binding domain, binds selectively to TNKS2 ARC4 with a potency of 8 uM, attenuates the WNT/β-catenin pathway in cells. |
