| Cat. No. |
Product Name |
Information |
| PC-72312 |
RP12146
PARP1/2 inhibitor
|
RP12146 (RP12146) is a novel, selective, and potent small molecule inhibitor of PARP1/2 with IC50 of 0.6/0.5 nM, with several fold selectivity over other isoforms. |
| PC-35442 |
Amelparib hydrochloric hydrate
|
Amelparib hydrochloric hydrate (JPI-289, JPI289) is a novel potent, water soluble PARP-1 inhibitor with IC50 of 18.5 nM, inhibits cellular PAR formation with IC50 of 10.7 nM. |
| PC-42353 |
Veliparib dihydrochloride
|
Veliparib (ABT-888) is a potent, BBB penetrant, and orally active PARP inhibitor with IC50 of 5.2 and 2.9 nM for PARP-1 and PARP-2, respectively. |
| PC-61976 |
NMS-P293
|
NMS-P293 is a novel potent and selective PARP-1 inhibitor possessing >200-fold selectivity versus PARP-2. |
| PC-60367 |
TNKS-IN-41
|
A highly potent and selective tankyrase inhibitor with pIC50 of 8.5 and 8.1 for TNKS1 and TNKS2, respectively. |
| PC-42683 |
MK-4827 tosylate
|
A highly potent PARP inhibitor with IC50 of 3.8 nM/2.1 nM for PARP1/PARP2. |
