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Cat. No. Product Name Information
PC-42682

MK-4827 hydrochloride

PARP1/2 inhibitor

Niraparib (MK-4827) hydrochloride is a highly potent PARP inhibitor with IC50 of 3.8 nM/2.1 nM for PARP1/PARP2.
PC-42681

Niraparib

PARP inhibitor

Niraparib (MK-4827, MK4827) is a highly potent PARP inhibitor with IC50 of 3.8 nM/2.1 nM for PARP1/PARP2.
PC-42678

A-966492

PARP inhibitor

A-966492 (A966492) is a highly potent and efficacious PARP inhibitor with Ki/EC50 of 1 nM/1 nM for PARP-1.
PC-25420

PARP15 inhibitor 7

PARP15 inhibitor

PARP15 inhibitor 7 is a selective inhibitor of mono-ART PARP15 with IC50 of 1.1 uM, inhibits PARP10 with IC50 of 2.4 uM, does not PARP2, TNKS2 and PARP14.
PC-25419

OUL245

PARP2 inhibitor

OUL245 is a potent, selective PARP2 inhibitor with IC50 of 44 nM, weakly inhibits multiple poly-ARTs at low μM concentration, does not inhibit mono-ARTs PARP7, PARP11, PARP12, PARP14, and PARP15.
PC-25418

OUL232

PARP10 inhibitor

OUL232 is a potent, selective inhibitor of mono-ARTs PARP7, PARP10, PARP11, PARP12, PARP14, and PARP15 with IC50 of 83 nM, 7.8 nM, 240 nM, 160 nM, 300 nM and 56 nM respectively.
PC-25417

PARP10-15 inhibitor 8l

PARP10 inhibitor

PARP10-15 inhibitor 8l (PARP10/15-IN-1) is a potent, dual inhibitor of mono-ADP-ribosyltransferases PARP10 and PARP15 with IC50 of 160 nM and 370 nM respectively, inactive against the other mono-ARTs, PARP12 and PARP16.
PC-25416

PARP10-15 inhibitor 8h

PARP10 inhibitor

PARP10-15 inhibitor 8h (PARP10/15-IN-2) is a potent, dual inhibitor of mono-ADP-ribosyltransferases PARP10 and PARP15 with IC50 of 150 nM and 370 nM respectively, inactive against the other mono-ARTs, PARP12 and PARP16.
PC-25415

OUL312

PARP10 inhibitor

OUL312 (OUL-312) is a potent, selective PARP10 inhibitor with IC50 of 20 nM, 75-fold selectivity over PARP15 (IC50=1500 nM).
PC-25071

Lotixparib

PARP-1 inhibitor

Lotixparib is a potent, selective PARP-1 inhibitor.
PC-25001

Mefuparib

PARP inhibitor

Mefuparib (CVL218) is a potent, highly selective, competitive PARP1/2 inhibitor with IC50 of 3.2/1.9 nM, respectively.
PC-24365

PARP14 inhibitor Q22

PARP14 inhibitor

PARP14 inhibitor Q22 is a highly potent, selective poly(ADP-ribose) polymerase 14 (PARP14) inhibitor with IC50 of 5.52 nM.

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