PARP compound (inhibitors, antagonists, modulators)-ProbeChem.com

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Cat. No.	Product Name	Information
PC-22045	K-476 TNKS1/2 inhibitor	K-476 is a highly potent and selective tankyrase (TNKS1/2) inhibitor, potently inhibits Wnt/β-catenin pathway with IC50 of 110 nM in cell-based luciferase assays.
PC-21163	PARP-1 inhibitor Pip5 PARP1 inhibitor	PARP-1 inhibitor Pip5 is an analog of PARP-1 type I inhibitor AZ0108, inhibits PARP-1 auto-PARylation with IC50 of 4-17 nM, shows similar type I inhibition of PARP-1 but is more cytotoxic than AZ0108.
PC-21009	kt-3283 PARP-HDAC inhibitor	kt-3283 is a novel bi-functional PARP-HDAC inhibitor with IC50 of 0.338 nM, 2.19 nM and 1.89 uM for PARP1, PARP2 and HDACs, respectively.
PC-35442	Amelparib hydrochloric hydrate	Amelparib hydrochloric hydrate (JPI-289, JPI289) is a novel potent, water soluble PARP-1 inhibitor with IC50 of 18.5 nM, inhibits cellular PAR formation with IC50 of 10.7 nM.
PC-61976	NMS-P293	NMS-P293 is a novel potent and selective PARP-1 inhibitor possessing >200-fold selectivity versus PARP-2.

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