| Cat. No. |
Product Name |
Information |
| PC-21621 |
Upamostat
uPA inhibitor
|
Upamostat is a serine protease inhibitor and orally bioavailable prodrug of WX-UK1, inhibit urokinase plasminogen activator (uPA) and the urokinase-type plasminogen activator (uPA) system. |
| PC-49102 |
IPR-3011
uPA inhibitor
|
IPR3011 is a small-molecule uPAR-uPA protein-protein interaction inhibitor with Ki of 2.4 uM. |
| PC-49101 |
WX-293
uPA inhibitor
|
WX-293 is a highly selective small-molecule inhibitor of urokinase-type plasminogen activator (uPA) with Ki of 2.4 uM. |
| PC-49100 |
WX‐340
uPA inhibitor
|
WX-340 is a highly specific and selective, peptidic cyclic competitive inhibitor of urokinase-type plasminogen activator (uPA) with Ki of 12 and 170 nM for human and mouse uPA, respectively, inhibit 10 Units of human uPA with IC50 of 90 nM. |
| PC-35131 |
TM5007
|
TM5007 is a poent inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 of 29 uM, exhibits no inhibitory activity against any of the closely related serpins or serine proteases at 250 uM. |
| PC-70342 |
CDE 096
|
CDE 096 (CDE-096, CDE096) is a selective, reversible, high-affinity PAI-1 inhibitor that prevents PAI-1 from inactivating tPA and uPA with similar potency (IC50=30 and 25 nM, respectively). |
| PC-60845 |
TM-5441
PAI-1 inhibitor
|
TM-5441 is a novel potent, orally active PAI-1 (plasminogen activator inhibitor-1) inhibitor that attenuates L-NAME-induced hypertension and vascular senescence in mice. |
| PC-60844 |
TM-5275
PAI-1 inhibitor
|
TM-5275 (TM5275) is a potent, orally active PAI-1 (plasminogen activator inhibitor-1) inhibitor with IC50 of 6.95 uM. |
| PC-42144 |
WX-UK1
|
WX-UK1 (UKI-1) is a small synthetic serine protease uPA (urokinase-type plasminogen activator) inhibitor that blocks tumor cell invasion, metastasis and primary tumor growth. |
| PC-42335 |
UK-371804
|
UK-371804 is a potent and selective inhibitor of urokinase-type plasminogen activator (uPA) with Ki of 10 nM. |
| PC-21332 |
TM5441
PAI-1 inhibitor
|
TM5441 is a specific, orally active, small molecule inhibitor of plasminogen activator inhibitor 1 (PAI-1, Serpin E1), TM5441 is as effective as complete deficiency of PAI-1 in protecting against L-NAME-induced pathologies. |
| PC-20179 |
UK122
uPA inhibitor
|
UK122 (UK-122) is potent, selective inhibitor of urokinase-type plasminogen activator (uPA) with IC50 0.2 uM in cell-free indirect uPA assays. |
