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Cat. No. Product Name Information
PC-42573

MK-2894 sodium

EP4 antagonist

MK-2894 sodium is a highly potent, selective, second generation prostaglandin E2 subtype 4 receptor (EP4) antagonist with Ki of 0.56 nM.
PC-42572

MK-2894

EP4 antagonist

MK-2894 (MK2894) is a highly potent, selective, second generation prostaglandin E2 subtype 4 receptor (EP4) antagonist with Ki of 0.56 nM.
PC-22638

Asapiprant

DP1 antagonist

Asapiprant (S-555739) is a potent and selective prostaglandin DP1 receptor antagonist with Ki of 0.44 nM, >300-fold selective over EP2 and other prostanoid receptors.
PC-22116

Travoprost

FP receptor agonist

Travoprost (Fluprostenol isopropyl ester), an isopropyl ester proagent, is a high affinity, selective FP prostaglandin full receptor agonist with Ki of 52 nM, functional EC50 of 27 nM.
PC-22027

L-902688

EP4 agonist

L-902688 (L-902,688) is a potent, selective and orally active EP4 receptor agonist with Ki of 0.38 nM and EC50 of 0.6 nM, >4,000-fold selective for EP4 over other EP and prostanoid receptors.
PC-21515

EP4R antagonist 77

EP4 antagonist

EP4R antagonist 77 is the sodium salt of EP4R antagonist 74, a potent, selective EP4 receptor antagonist with Ki of 11.2 nM.
PC-21514

EP4R antagonist 74

EP4 antagonist

EP4R antagonist 74 is a potent, selective EP4 receptor antagonist with Ki of 11.2 nM, shows apparent dissociation constant KB of 16 nM in functional cAMP production-based assays.
PC-21493

Cicaprost

IP agonist

Cicaprost (ZK 96480) is a potent prostacyclin receptor (IP) agonist, causes a concentration-dependent relaxation of the artery with EC50 of 5.8 nM.
PC-21315

Ramatroban

TxA2 inhibitor

Ramatroban (BAY u3405) is a potent selective thromboxane A2 (TxA2) antagonist with IC50 of 14 nM, also antagonizes CRTH2 (IC50=113 nM) by inhibiting PGD2 binding.
PC-21314

AZD1981

DP2 (CRTh2) inhibitor

AZD1981 is a potent and selective CRTh2 (DP2) antagonist with pIC50 of 8.4 (human recombinant DP2), with no significant affinity towards recombinant human DP1 receptors.
PC-21037

TPST-1495

EP2/EP4 antagonist

TPST-1495 (TPST1495) is a potent, selective, orally available dual EP2/EP4 PGE2 receptor antagonist with IC50 of 17.21/3.24 nM, respectively.
PC-20915

Selexipag

IP receptor agonist

Selexipag (NS-304) is an orally available, long-acting nonprostanoid prostacyclin receptor (IP receptor) agonist, the prodrug of the active form of MRE-269.

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