| Cat. No. |
Product Name |
Information |
| PC-35079 |
OBE022
PGF2α receptor antagonist
|
OBE022 (Ebopiprant, OBE-022) is a potent, highly selective, orally active antagonist of the contractile PGF2α prostaglandin receptor with Kb of 5.9 nM, shows no activity for other human PG receptors subtypes. |
| PC-63545 |
E7046
EP4 antagonist
|
E7046 (Palupiprant, ER-886046) is a potent, selective, orally bioavailable EP4 receptor antagonist with IC50 of 13.5 nM, Ki of 23.14 nM. |
| PC-63431 |
ADC-3680
CRTH2 inhibitor
|
ADC-3680 (PTR-36, ADC-3680B) is a potent, selective prostaglandin D2 receptor (DP2, CRTH2) antagonist for the treatment of asthma.. |
| PC-63430 |
MK-1029
CRTH2 inhibitor
|
MK-1029 is a potent, selective prostaglandin D2 receptor (DP2, CRTH2) antagonist for the treatment of asthma. |
| PC-63350 |
GSK726701A
EP4 agonist
|
GSK726701A is a novel potent, selective EP4 receptor partial agonist with pEC50 of 7.4 in cAMP accumulation assay, >100-fold against a set of other prostaglandin receptors (EP1-3, DP1, FP, IP and TP). |
| PC-43293 |
Dinoprost tromethamine salt
|
Dinoprost (Prostaglandin F2α, PGF2α) is a naturally occurring prostaglandin used to induce labor and as an abortifacient, causes contraction of vascular, bronchial, intestinal, and myometrial smooth muscle, and also exhibits potent luteolytic activity.. |
| PC-43292 |
Dinoprost
|
Dinoprost (Prostaglandin F2α, PGF2α) is a naturally occurring prostaglandin used to induce labor and as an abortifacient, causes contraction of vascular, bronchial, intestinal, and myometrial smooth muscle, and also exhibits potent luteolytic activity. |
| PC-63165 |
ONO-8055
EP2/EP3 agonist
|
ONO-8055 is a highly selective and potent EP2/EP3 dual agonist with EC50 of 0.67/0.7 nM, shows >450-fold selectivity over EP4 receptors (EC50=339 nM). |
| PC-63012 |
MF266-1
EP1 antagonist
|
MF266-1 is a potent, selective prostaglandin E receptor subtype 1 (EP1) antagonist with Ki of 3.8 nM, displayes a relatively good selectivity over other prostanoid receptors. |
| PC-63011 |
MF266-3
EP3 antagonist
|
MF266-3 is a potent, selective prostaglandin E receptor subtype 3 (EP3) antagonist with Ki of 0.8 nM. |
| PC-62041 |
U-46619
TP agonist
|
U-46619 is a potent and stable thromboxane A2 (TP) receptor agonist with EC50 of 35 nM. |
| PC-62029 |
TG4-155
EP2 antagonist
|
TG4-155 is a potent and selective prostaglandin EP2 receptor antagonist with Kb of 2.4 nM. |
