| Cat. No. |
Product Name |
Information |
| PC-21514 |
EP4R antagonist 74
EP4 antagonist
|
EP4R antagonist 74 is a potent, selective EP4 receptor antagonist with Ki of 11.2 nM, shows apparent dissociation constant KB of 16 nM in functional cAMP production-based assays. |
| PC-21493 |
Cicaprost
IP agonist
|
Cicaprost (ZK 96480) is a potent prostacyclin receptor (IP) agonist, causes a concentration-dependent relaxation of the artery with EC50 of 5.8 nM. |
| PC-21315 |
Ramatroban
TxA2 inhibitor
|
Ramatroban (BAY u3405) is a potent selective thromboxane A2 (TxA2) antagonist with IC50 of 14 nM, also antagonizes CRTH2 (IC50=113 nM) by inhibiting PGD2 binding. |
| PC-21314 |
AZD1981
DP2 (CRTh2) inhibitor
|
AZD1981 is a potent and selective CRTh2 (DP2) antagonist with pIC50 of 8.4 (human recombinant DP2), with no significant affinity towards recombinant human DP1 receptors. |
| PC-21037 |
TPST-1495
EP2/EP4 antagonist
|
TPST-1495 (TPST1495) is a potent, selective, orally available dual EP2/EP4 PGE2 receptor antagonist with IC50 of 17.21/3.24 nM, respectively. |
| PC-20855 |
L001
EP4 antagonist
|
L001 is a potent and selective EP4 antagonist with cAMP IC50 of 7.29 nM, impairs pancreatic cancer migration and invasion. |
| PC-20852 |
AMX12006
EP4 antagonist
|
AMX12006 (AMX-12006) is a potent, selective, orally active antagonist of prostaglandin E2 (PGE2) receptor 4 (EP4) with IC50 of 4.3 nM in cAMP assays, shows no activity against EP1, EP2, EP3 receptors. |
| PC-20722 |
SQ-29548
TP antagonist
|
SQ-29548 (SQ-29,548) is a potent and specific antagonist of thromboxane-prostanoid (TP) receptor with binding Ki value of 4.1 nM. |
| PC-20715 |
Ifetroban sodium
TP antagonist
|
Ifetroban sodium (BMS-180291, CPI211) is a potent and highly selective antagonist of thromboxane A2/prostaglandin endoperoxide (TP) receptors, inhibits platelet aggregation induced by arachidonate (800 uM) and U-46,619 (10 uM) with IC50 of 7 and 21 nM, respectively. |
| PC-20529 |
AGN 225660
Prostaglandin Receptor antagonist
|
AGN 225660 is a second-generation prostanoid receptor antagonist acting at multiple receptor subtypes with IC50 of 220/70/2900/7100/70/180/1100/5 nM for DP1/EP1/EP2/EP3/EP4/FP/IP/TP receptors, respectively. |
| PC-20528 |
AS604872
FP antagonist
|
AS604872 is a potent and selective prostaglandin F2α receptor (FP) antagonist with a Ki of 35 nM, 158 nM and 323 nM for human, rat and mouse FP receptors, respectively. |
| PC-20527 |
SC-51322
EP1 antagonist
|
SC-51322 is a potent and selective antagonist of prostaglandin E2 (PGE2) receptor (EP1) with pA2 of 8.1. |
