| Cat. No. |
Product Name |
Information |
| PC-25878 |
BW245C
DP1 receptor agonist
|
BW 245C is a potent prostaglandin PGD2 analogue and selective prostanoid DP-receptor (DP1) agonist. |
| PC-25367 |
Treprostinil
DP1/EP2 agonist, DHHC9 inhibitor
|
Treprostinil (UT-15) is a potent DP1 and EP2 agonist with EC50 of 0.6 nM and 6.2 nM, respectively, also is a potent DHHC9 inhibitor that effectively suppressed adenocarcinoma cell migration. |
| PC-24814 |
Ralinepag
IP receptor agonist
|
Ralinepag (APD811) is a potent, selective, orally bioavailable and non-prostanoid prostacyclin receptor (IP) agonist with EC50 of 8.5 nM and 530 nM for human and rat IP receptors respectively, inhibits ADP-induced human platelet aggregation with IC50 of 38 nM. |
| PC-24139 |
Irodanoprost sodium
EP4 agonist
|
Irodanoprost sodium is a potent, selective small-molecule agonist of the prostaglandin E2 type 4 (EP4) receptor. |
| PC-24138 |
Irodanoprost
EP4 agonist
|
Irodanoprost is a potent, selective small-molecule agonist of the prostaglandin E2 type 4 (EP4) receptor. |
| PC-24012 |
Latanoprost
FP receptor agonist
|
Latanoprost (PHXA41) is a prostaglandin F2α analogue and prostaglandin FP receptor agonist, increases uveoscleral outflow of aqueous humor. |
| PC-24011 |
Bimatoprost
Prostaglandin FP receptor agonist
|
Bimatoprost (AGN 192024) is a prostaglandin analog and prostaglandin FP receptor agonist with Ki of 6.3 uM, reduces intraocular pressure by regulating scleral and trabecular outflow. |
| PC-23531 |
Seratrodast
TXA2 antagonist, Ferroptosis inhibitor
|
Seratrodast (AA2414) is a potent, specific thromboxane A2 (TXA2) receptor antagonist, competitively inhibits the contractile response to U-46619 in guinea pig tracheal and parenchymal strips and dog saphenous vein strips with pA2 values of 7.69, 8.29 and 6.79, respectively, also inhibits ferroptosis. |
| PC-22638 |
Asapiprant
DP1 antagonist
|
Asapiprant (S-555739) is a potent and selective prostaglandin DP1 receptor antagonist with Ki of 0.44 nM, >300-fold selective over EP2 and other prostanoid receptors. |
| PC-22116 |
Travoprost
FP receptor agonist
|
Travoprost (Fluprostenol isopropyl ester), an isopropyl ester proagent, is a high affinity, selective FP prostaglandin full receptor agonist with Ki of 52 nM, functional EC50 of 27 nM. |
| PC-22027 |
L-902688
EP4 agonist
|
L-902688 (L-902,688) is a potent, selective and orally active EP4 receptor agonist with Ki of 0.38 nM and EC50 of 0.6 nM, >4,000-fold selective for EP4 over other EP and prostanoid receptors. |
| PC-21515 |
EP4R antagonist 77
EP4 antagonist
|
EP4R antagonist 77 is the sodium salt of EP4R antagonist 74, a potent, selective EP4 receptor antagonist with Ki of 11.2 nM. |
