| Cat. No. |
Product Name |
Information |
| PC-27722 |
ONO-AP-324
EP3 agonist
|
ONO-AP-324 is a potent and selective prostanoid EP3 receptor agonist. |
| PC-27581 |
Iloprost
IP/EP1 agonist
|
Iloprost (ZK 36374, Ciloprost) is a selective EP1-/IP-receptor agonist, inhibits the FMLP-induced increase in [Ca2+]i with IC50 of 38 nM. |
| PC-27580 |
Butaprost
EP2 agonist
|
Butaprost (TR4979) is a highly selective prostaglandin E receptor (EP2) agonist with EC50 of 33 nM, and Ki of 2.4 uM for murine EP2 receptor. |
| PC-27072 |
Evatanepag
EP2 receptor agonist
|
Evatanepag (CP-533536, CP-533,536) is a highly selective and potent functional EP2 receptor agonist with high affinity to rat EP2 receptor (IC50=50 nM), is >50-fold more selective over EP4 receptor subtype. |
| PC-27006 |
TP-18
EP2/EP4 antagonist
|
TP-18 is a potent, selective, orally available dual PGE2 receptor EP2/EP4 antagonist with IC50 of 9.5/3.3 nM respectively. |
| PC-26606 |
SC-51089
EP1 antagonist
|
SC-51089 (SC51089) is a selective antagonist of prostaglandin E2 EP1 receptor, with Ki values of 1.3, 11.2, 17.5, and 61.1 μM for EP1, TP, EP3, and FP receptors, respectively, exhibits neuroprotective activity. |
| PC-26564 |
BPN-37440
EP2 antagonist
|
BPN-37440 is a potent, selective prostaglandin-E2 receptor EP2 antagonist with IC50 of 53 nM, with no activity against DP1, EP4 and IP receptors. |
| PC-25878 |
BW245C
DP1 receptor agonist
|
BW 245C is a potent prostaglandin PGD2 analogue and selective prostanoid DP-receptor (DP1) agonist. |
| PC-25367 |
Treprostinil
DP1/EP2 agonist, DHHC9 inhibitor
|
Treprostinil (UT-15) is a potent DP1 and EP2 agonist with EC50 of 0.6 nM and 6.2 nM, respectively, also is a potent DHHC9 inhibitor that effectively suppressed adenocarcinoma cell migration. |
| PC-24814 |
Ralinepag
IP receptor agonist
|
Ralinepag (APD811) is a potent, selective, orally bioavailable and non-prostanoid prostacyclin receptor (IP) agonist with EC50 of 8.5 nM and 530 nM for human and rat IP receptors respectively, inhibits ADP-induced human platelet aggregation with IC50 of 38 nM. |
| PC-24139 |
Irodanoprost sodium
EP4 agonist
|
Irodanoprost sodium is a potent, selective small-molecule agonist of the prostaglandin E2 type 4 (EP4) receptor. |
| PC-24138 |
Irodanoprost
EP4 agonist
|
Irodanoprost is a potent, selective small-molecule agonist of the prostaglandin E2 type 4 (EP4) receptor. |
