| Cat. No. |
Product Name |
Information |
| PC-45111 |
TG6-10-1
EP2 antagonist
|
TG6-10-1 is a potent and selective antagonist of prostaglandin E2 receptor subtype EP2 with Kb of 17.8 nM. |
| PC-45579 |
PF-04418948
EP2 antagonist
|
PF-04418948 (PF 04418948) is a novel potent and selective prostaglandin EP2 receptor antagonist. |
| PC-45077 |
Grapiprant
EP4 antagonist
|
Grapiprant (CJ-023423, AAT-007) is a potent, selective EP4 receptor antagonist with Ki values of 13/20 nM against human and rat EP(4) receptors. |
| PC-42573 |
MK-2894 sodium
EP4 antagonist
|
MK-2894 sodium is a highly potent, selective, second generation prostaglandin E2 subtype 4 receptor (EP4) antagonist with Ki of 0.56 nM. |
| PC-42572 |
MK-2894
EP4 antagonist
|
MK-2894 (MK2894) is a highly potent, selective, second generation prostaglandin E2 subtype 4 receptor (EP4) antagonist with Ki of 0.56 nM. |
| PC-24012 |
Latanoprost
FP receptor agonist
|
Latanoprost (PHXA41) is a prostaglandin F2α analogue and prostaglandin FP receptor agonist, increases uveoscleral outflow of aqueous humor. |
| PC-24011 |
Bimatoprost
Prostaglandin FP receptor agonist
|
Bimatoprost (AGN 192024) is a prostaglandin analog and prostaglandin FP receptor agonist with Ki of 6.3 uM, reduces intraocular pressure by regulating scleral and trabecular outflow. |
| PC-23531 |
Seratrodast
TXA2 antagonist, Ferroptosis inhibitor
|
Seratrodast (AA2414) is a potent, specific thromboxane A2 (TXA2) receptor antagonist, competitively inhibits the contractile response to U-46619 in guinea pig tracheal and parenchymal strips and dog saphenous vein strips with pA2 values of 7.69, 8.29 and 6.79, respectively, also inhibits ferroptosis. |
| PC-22638 |
Asapiprant
DP1 antagonist
|
Asapiprant (S-555739) is a potent and selective prostaglandin DP1 receptor antagonist with Ki of 0.44 nM, >300-fold selective over EP2 and other prostanoid receptors. |
| PC-22116 |
Travoprost
FP receptor agonist
|
Travoprost (Fluprostenol isopropyl ester), an isopropyl ester proagent, is a high affinity, selective FP prostaglandin full receptor agonist with Ki of 52 nM, functional EC50 of 27 nM. |
| PC-22027 |
L-902688
EP4 agonist
|
L-902688 (L-902,688) is a potent, selective and orally active EP4 receptor agonist with Ki of 0.38 nM and EC50 of 0.6 nM, >4,000-fold selective for EP4 over other EP and prostanoid receptors. |
| PC-21515 |
EP4R antagonist 77
EP4 antagonist
|
EP4R antagonist 77 is the sodium salt of EP4R antagonist 74, a potent, selective EP4 receptor antagonist with Ki of 11.2 nM. |
