| Cat. No. |
Product Name |
Information |
| PC-61565 |
MK-7246
CRTH2/GPR44 inhibitor
|
MK-7246 is a potent, selectie, orally available prostaglandin D2 receptor (CRTH2, GPR44) antagonist with Ki of 2.5 nM (hCRTH2). |
| PC-61564 |
TASP0376377
CRTH2 inhibitor
|
TASP0376377 is a potent, selective prostaglandin D2 receptor (CRTH2) antagonist with binding IC50 of 19 nM. |
| PC-61563 |
BI 671800
CRTH2 inhibitor
|
BI 671800 is a potent, oral prostaglandin D2 receptor (DP2/CRTH2) antagonist with IC50 of 4.5 nM and 3.7 nM for PGD2 binding to CRTH2 in hCRTH2 and mCRTH2 transfected cells, respectively. |
| PC-61555 |
ER-819762
EP4 antagonist
|
ER-819762 is a novel potent, selective, orally active EP4 receptor antagonist with IC50 of 59 nM in cAMP-dependent reporter assay. |
| PC-61499 |
AAT-008
EP4 antagonist
|
AAT-008 is a potent, and selective prostaglandin EP4 receptor antagonist with binding IC50 of 2.4 nM. |
| PC-60722 |
BMY 45778
Prostacyclin agonist
|
BMY 45778 is a potent, non-prostanoid prostacyclin partial agonist that potently inhibits human (IC50=35 nM), rabbit (IC50=136 nM) and rat (IC50=1.3 uM) platelet aggregation. |
| PC-60721 |
ONO-1301
Prostacyclin agonist
|
ONO-1301 is a stable, orally active, non-prostanoid prostacyclin I2 (PGI2) mimetic and prostacyclin agonist with inhibitory activity against thromboxane A2 synthase. |
| PC-60673 |
AM211
DP2 antagonist
|
AM211 (AM-211) is a potent, selective and orally bioavailable prostaglandin D2 receptor type 2 (DP2) antagonist with IC50 of 4.9 nM for human DP2. |
| PC-70016 |
AH-23848 calcium salt
TP1/EP4 antagonist
|
AH-23848 calcium salt is a dual antagonist of TP1 and EP4 receptors that inhibit TXA2-induced platelet aggregation with IC50 of 0.26 uM. |
| PC-42574 |
AH6809
EP/DP receptor antagonist
|
AH6809 is a xanthone derivative that fuctions as an EP and DP receptor antagonist with Ki of 1217, 1150, 1597, and 1415 nM for the cloned human EP1, EP2, EP3-III, and DP receptor respectively. |
| PC-45075 |
Fevipiprant
CRTH2 inhibitor
|
Fevipiprant (NVP-QAW039, QAW-039) is a potent, selective, slowly dissociating CRTh2 antagonist with Kd of 1.14 nM. |
| PC-42700 |
CJ-042794
EP4 antagonist
|
CJ-042794 (CJ-42794, RQ-15986) is a potent, selective prostaglandin E receptor subtype 4 (EP4) antagonist with pKi of 8.5. |
