| Cat. No. |
Product Name |
Information |
| PC-26009 |
TRAP-14
PAR-1 agonist
|
TRAP-14 is a specific thrombin receptor (protease-activated receptor-1, PAR-1) agonist peptide, mimics the effect of thrombin on platelets. |
| PC-25600 |
Punicalagin
PAR2 antagonist, 3CLpro inhibitor, Dhx9 inhibitor
|
Punicalagin is a major polyphenol enriched in pomegranat, a reversible and non-competitive 3CLpro inhibitor and inhibits SARS-CoV-2 replication in vitro, has antioxidant, anti-inflammatory and anticancer effects, also is a potent protease-activated receptor-2 (PAR2) inhibitor with IC50 of 1.5 uM. |
| PC-25413 |
E6795
PAR-2 inhibitor
|
E6795 (E-6795) is a potent, selective and orally available protease-activated receptor 2 (PAR-2) inhibitor with IC50 of 6.56 nM in cell-based calcium influx assays. |
| PC-22246 |
SLIGKV-NH2
PAR2 agonist
|
SLIGKV-NH2 is a highly potent protease-activated receptor-2 (PAR2) activating peptide. |
| PC-21762 |
1-Piperidine Propionic Acid
PAR2 inhibitor
|
1-Piperidine Propionic Acid (1-PPA) is an allosteric Inhibitor of protease activated receptor-2 (PAR2) with IC50 of 2.3 uM. |
| PC-20965 |
BMS-986141
PAR4 inhibitor
|
BMS-986141 is a potent, selective antagonist of protease-activated receptor 4 (PAR4) with IC50 of 0.4 nM, Kd of 0.1 nM. |
| PC-20576 |
NRD-21
PAR1 modulator
|
NRD-21 is a potent, selective, reversible, negative allosteric modulator of PAR1 with IC50 of 0.37 uM in calcium mobilization assays. |
| PC-49647 |
PAR1 inhibitor Q94
PAR1 antagonist
|
Q94 is a selective PAR1 antagonist and allosteric modulator that selectively block PAR(1) /Gα(q) interaction and signalling. |
| PC-73008 |
UDM-001651
PAR4 inhibitor
|
UDM-001651 (UDM001651) is a potent, selective, and orally bioavailable PAR4 antagonist with IC50 of 2.4 nM. |
| PC-72283 |
PAR2 antagonist C391
PAR2 antagonist
|
PAR2 antagonist C391 (C391) is a selective PAR2 antagonist, potently inhibits peptidomimetic-induced PAR2 Ca2+ signalling with IC50 of 1.3 uM. |
| PC-38310 |
I-287
PAR2 antagonist
|
I-287 is a potent, selective, orally active inhibitor of PAR2, negative PAR2 allosteric modulator, inhibits PAR2-mediated activation of Gq and G12/13 but not Gi/o proteins (IC50=45-390 nM). |
| PC-60320A |
AZ8838 racemate
PAR2 inhibitor
|
AZ8838 racemate (AZ-8838 racemate) is the racemate form of AZ8838, which is a potent, and selective PAR2 antagonist with Kd of 125 nM.. |
