| Cat. No. |
Product Name |
Information |
| PC-21764 |
BIX 02565
RSK2 inhibitor
|
BIX 02565 is a potent, selective ribosomal S6 kinase 2 (RSK2) inhibitor with IC50 of 1.1 nM. |
| PC-49024 |
PF-4708671
S6K1 inhibitor
|
PF-4708671 is a potent, specific, cell-permeable inhibitor of S6K1 (p70 ribosomal S6 kinase 1), inhibits the activity of full-length S6K1 in vitro with Ki of 20 nM, and S6K1 isolated from IGF1-stimulated HEK293 cells with IC50 of 160 nM. |
| PC-72701 |
S6K2 inhibitor Compound 2
S6K2 inhibitor
|
S6K2 inhibitor Compound 2 is the first potent and highly isoform-specific S6K2 inhibitor with IC50 of 22 nM, inactive for the closely related isoform S6K1 at 5 uM. |
| PC-72284 |
PMD-026
RSK inhibitor
|
PMD-026 (PMD026) is an oral, reversible small molecule inhibitor of ribosomal S6 kinases (RSK1-4) with IC50 of 2 nM (RSK1), 0.7 nM (RSK2), 0.9 nM (RSK3) and 2 nM (RSK4). |
| PC-43060 |
LY-2584702 hydrochloride
p70S6K1 inhibitor
|
LY2584702 is a potent, selective, ATP-competitive inhibitor of P70S6 kinase-1 (p70S6K1) with IC50 of 4 nM. |
| PC-43059 |
LY-2584702 tosylate
p70S6K1 inhibitor
|
LY-2779964 (LY2584702 tosylate) is a potent, selective, ATP-competitive inhibitor of P70 S6 kinase-1 (p70S6K1) with IC50 of 4 nM. |
| PC-43058 |
LY-2584702
p70S6K1 inhibitor
|
LY2584702 is a potent, selective, ATP-competitive inhibitor of P70 S6 kinase-1 (p70S6K1) with IC50 of 4 nM. |
| PC-62854 |
RSK2-IN-20
RSK2 inhibitor
|
RSK2-IN-20 is a potent, selective, and durable inhibitpr of RSK2 with IC50 of 47 nM. |
| PC-62045 |
BRD 7389
RSK inhibitor
|
BRD 7389 is an inhibitor of ribosomal S6 kinases (RSK) with IC50 of 1.5 uM, 2.4 uM, and 1.2 uM for RSK1, RSK2, and RSK3, respectively. |
| PC-60433 |
M2698
S6K/Akt inhibitor
|
M2698 (MSC2363318A) is a potent, selective, ATP-competitive, orally bioavailable and brain penetrant dual inhibitor of p70S6K and Akt1/3 with IC50 of 1 nM and 17 nM, respectively. |
| PC-70183 |
SL0101
RSK inhibitor
|
SL0101 (SL 0101-1) is the first specific inhibitor of RSK (p90 ribosomal S6 kinase) with IC50 of 89 nM for RSK2. |
| PC-45678 |
LJI308
RSK inhibitor
|
LJI308 (LJI 308) is a potent and specific pan-RSK inhibitor with IC50s of 6 nM, 4 nM and 13 nM for RSK1, RSK2 and RSK3 respectively. |
