| Cat. No. |
Product Name |
Information |
| PC-21582 |
NVS-STG2
STING agonist
|
NVS-STG2 is a small molecule STING agonist with AC50 of 5.2 uM in ISRE-Luc reporter assays, induces STING-dependent IRF3 phosphorylation in THP1 cells. |
| PC-20020 |
SB24011
STING-TRIM29 inhibitor
|
SB24011 (SB 24011) is a selective small molecule inhibitor of the STING-TRIM29 interaction with IC50 of 3.85 uM in luciferase complementation assays, enhances cGAMP-mediated STING immunity. |
| PC-49595 |
HB3089
STING agonist
|
HB3089 (HB-3089) is a novel potent, highly specific STING agonist, dose-dependently activates interferon-stimulated gene (ISG) signaling in THP1-Dual reporter cells with EC50 of 1-10 uM. |
| PC-49313 |
BSP16
STING agonist
|
BSP16 (LF250) is a potent, orally available STING agonist, strongly activates STING signaling in human and mouse cells and binds STING as a homodimer. |
| PC-38729 |
SHR1032
STING agonist
|
SHR1032 is a novel small molecule non-cyclic di-nucleotide STING agonist, exhibits significantly high affinity binding to STING and cellular reporter assay (EC50=30 nM). |
| PC-38565 |
STING inhibitor C-170
STING inhibitor
|
STING inhibitor C-170 is a small-molecule STING inhibitor, efficiently inhibited both hsSTING and mmSTING. |
| PC-73371 |
MSA-2
STING agonist
|
MSA-2 is a potent and orally available non-nucleotide STING agonist with EC50 of 8.3 and 24 uM for human STING isoforms WT and HAQ, respectively. |
| PC-73370 |
STING activator Compound 8
STING agonist
|
STING activator Compound 8 is a potent, small molecule activator/agonist of human STING with EC50 of 122 nM (HEK, R232), HAQ STING EC50 of 944 nM. |
| PC-73369 |
STING activator Compound 11
STING agonist
|
STING activator Compound 11 is a potent, small molecule activator/agonist of human STING with EC50 of 66 nM (HEK, R232). |
| PC-73368 |
STING activator Compound 53
STING agonist
|
STING activator Compound 53 is a potent small molecule activator of human STING with functional EC50 of 183 nM in immortalised and primary cells. |
| PC-73361 |
G150
cGAS inhibitor
|
G150 is a potent, specific human cyclic GMP-AMP synthase (cGAS) small-molecule inhibitor with IC50 of 10.2 nM, shows no inhibition against m-cGAS. |
| PC-73360 |
G140
cGAS inhibitor
|
G140 is a potent, specific human cGAS small-molecule inhibitor with IC50 of 14.0 nM and 442 nM for h-cGAS and m-cGAS, respectively. |
