| Cat. No. |
Product Name |
Information |
| PC-60187 |
Cridanimod sodium
STING agonist
|
Cridanimod sodium (XBIO-101) is a potent type I interferon (IFN) inducer that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route. |
| PC-60186 |
Cridanimod
STING agonist
|
Cridanimod (10-CMA, XBIO-101, CMA) is a potent type I interferon (IFN) inducer that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route. |
| PC-45676 |
STING agonist G10
STING agonist
|
G10 (STING agonist G10) is a novel human-specific STING agonist; triggers IRF3/IFN-associated transcription in human fibroblasts. |
| PC-42754 |
DMXAA
STING agonist
|
DMXAA (ASA-404, Vadimezan) is a vascular disrupting agent (VDA) and competitive inhibitor of DT-diaphorase with Ki of 20 uM, also is a partial STING agonist, competes for human STING activation and STING dependent innate immune pathways. |
| PC-24987 |
STING activator diABZI-a1
STING agonist
|
STING activator diABZI-a1 is a potent, small molecule activator of STING, elicits IFNβ in human PBMCs with EC50 of 117 nM. |
| PC-24986 |
STING inhibitor diABZI-i
STING inhibitor
|
STING inhibitor diABZI-I (STING-IN-6) is a potent, small molecule inhibitor of STING, inhibits cGAMP-induced IFNβ in PBMCs with IC50 of 49 nM. |
| PC-24981 |
STING inhibitor 18
STING inhibitor
|
STING inhibitor 18 is a potent, orthosteric STING inhibitor / antagonist with IC50 of 68 nM in HAQ STING cGAMP displacement assay. |
| PC-24980 |
STING inhibitor THIQi
STING inhibitor
|
STING inhibitor THIQi is a potent, orthosteric STING inhibitor with IC50 of 84 nM in HAQ STING cGAMP displacement assays, inhibits cGAMP-induced IFNβ in PBMCs with IC50 of 29 nM. |
| PC-24871 |
Clonixeril
STING inhibitor
|
Clonixeril (CXL) is a highly potent, non-nucleotide hSTING modulator, has two modes of interaction with hSTING, shows weak agonist activity at micromolar concentrations, acts as a hSTING antagonist at <1 nM (EC50 < 1fM). |
| PC-24803 |
SR-301
STING agonist
|
SR-301 is a potent, non-nucleotide, oral small-molecule STING agonist with EC50 of 0.6 uM. |
| PC-24802 |
ZSA-215
STING agonist
|
ZSA-215 is a potent oral STING agonist with EC50 of 3.3 uM, enhances STING signaling through promoting the phosphorylation of STING and interferon regulatory factor 3 (IRF3) and secretion of IFN-β. |
| PC-24614 |
TAK-676
STING agonist
|
TAK-676 (Dazostinag disodium) is a potent, selective stimulator of interferon genes (STING) agonist with highly selective binding and activation of STING proteins from various species, with Kd values of 0.01 uM, 0.008 uM, 0.011 uM, and 0.027 uM for mouse, rat, cynomolgus monkey, and human STING orthologs, respectively. |
