| Cat. No. |
Product Name |
Information |
| PC-60187 |
Cridanimod sodium
STING agonist
|
Cridanimod sodium (XBIO-101) is a potent type I interferon (IFN) inducer that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route. |
| PC-60186 |
Cridanimod
STING agonist
|
Cridanimod (10-CMA, XBIO-101, CMA) is a potent type I interferon (IFN) inducer that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route. |
| PC-45676 |
STING agonist G10
STING agonist
|
G10 (STING agonist G10) is a novel human-specific STING agonist; triggers IRF3/IFN-associated transcription in human fibroblasts. |
| PC-42754 |
DMXAA
STING agonist
|
DMXAA (ASA-404, Vadimezan) is a vascular disrupting agent (VDA) and competitive inhibitor of DT-diaphorase with Ki of 20 uM, also is a partial STING agonist, competes for human STING activation and STING dependent innate immune pathways. |
| PC-24803 |
SR-301
STING agonist
|
SR-301 is a potent, non-nucleotide, oral small-molecule STING agonist with EC50 of 0.6 uM. |
| PC-24802 |
ZSA-215
STING agonist
|
ZSA-215 is a potent oral STING agonist with EC50 of 3.3 uM, enhances STING signaling through promoting the phosphorylation of STING and interferon regulatory factor 3 (IRF3) and secretion of IFN-β. |
| PC-24614 |
TAK-676
STING agonist
|
TAK-676 (Dazostinag disodium) is a potent, selective stimulator of interferon genes (STING) agonist with highly selective binding and activation of STING proteins from various species, with Kd values of 0.01 uM, 0.008 uM, 0.011 uM, and 0.027 uM for mouse, rat, cynomolgus monkey, and human STING orthologs, respectively. |
| PC-24613 |
MK-2118
STING agonist
|
MK-2118 is a highly potent, noncyclic dinucleotide STING agonist. |
| PC-24587 |
HG381
STING agonist
|
HG381 is a new-generation, non-CDN STING agonist. |
| PC-24586 |
STING agonist A4
STING agonist
|
STING agonist A4 is a potent, specific STING agonist, effectively activates STING in both human THP1 and mouse RAW 264.7 cells with EC50 values of 0.06 and 14.15 μM, respectively. |
| PC-24560 |
STING agonist 12b
STING agonist
|
STING agonist 12b is a small molecule STING agonist with EC50 of 7.45 uM and 10.23 uM for human and murine STING respectively and Emax>100% for both, directly binds to carboxy-terminal domain (CTD) (IC50=1.92 uM) and stabilizes the hSTING protein. |
| PC-24559 |
STING synergist 67
STING synergist
|
STING synergist 67 is a selective STING synergist with EC50 of 20.5 uM, binds to carboxy-terminal domain (CTD) of STING (SPR KD=12.2 uM), amplifies cGAMP-induced pathway activation without inherent agonist properties. |
