| Cat. No. |
Product Name |
Information |
| PC-62639 |
ADU-S100 disodium salt
STING agonist
|
ADU-S100 (MIW815, ML RR-S2 CDA) disodium salt is a synthetic cyclic dinucleotide derivative that functions as a highly potent agonist of STING, enhances binding affinity to STING and activates all known human STING alleles. |
| PC-61228 |
STING agonist C11
STING agonist
|
STING agonist C11 is a novel cell-permeable STING agonist that activates IFN-dependent signaling processes and induces IFN secretion from human cells. |
| PC-60187 |
Cridanimod sodium
STING agonist
|
Cridanimod sodium (XBIO-101) is a potent type I interferon (IFN) inducer that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route. |
| PC-60186 |
Cridanimod
STING agonist
|
Cridanimod (10-CMA, XBIO-101, CMA) is a potent type I interferon (IFN) inducer that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route. |
| PC-45676 |
STING agonist G10
STING agonist
|
G10 (STING agonist G10) is a novel human-specific STING agonist; triggers IRF3/IFN-associated transcription in human fibroblasts. |
| PC-42754 |
DMXAA
STING agonist
|
DMXAA (ASA-404, Vadimezan) is a vascular disrupting agent (VDA) and competitive inhibitor of DT-diaphorase with Ki of 20 uM, also is a partial STING agonist, competes for human STING activation and STING dependent innate immune pathways. |
| PC-26653 |
SH-273
STING agonist, PI3Kγ inhibitor
|
SH-273 is a dual functional compound that simultaneously activate STING and inhibit PI3Kγ, stimulates STING activity (IC50=29.6 nM) in THP-1 Blue ISG cells (STING reporter) and inhibited PI3Kγ (IC50=20.2 nM). |
| PC-26652 |
STING inhibitor Y-320
STING inhibitor
|
Y-320 is a specific, allosteric small-molecule STING inhibitor, inhibits IL-17 production by CD4 T cells stimulated with IL-15 with IC50 of 20-60 nM, blocks STING Golgi translocation and downstream signaling. |
| PC-26568 |
KSI-028
STING inhibitor
|
KSI-028 is a potent, specific STING inhibitor with IC50 of 0.652 uM in reporter assay in RAW264.7 cells. |
| PC-26425 |
UM-200
STING inhibitor
|
UM-200 is a specific small molecule inhibitor of cGAS-STING pathway with EC50 of 1.1 uM in THP1-Dual cells that overexpress wild-type STING, blocks STING oligomerization, inhibits STING activation and signaling. |
| PC-25518 |
Salvianolic acid A
STING modulator
|
Salvianolic acid A (SAL A, SAA) is a phenolic acid substance extracted from the plant Salvia miltiorrhiza Bunge, possessing antioxidant, neuroprotective effects, and anti-platelet aggregation properties, also effectively inhibits LCMV infection as a cap-dependent endonuclease inhibitor, also directly interacts with STING and regulates the TBK1/IRF3 signaling pathway. |
| PC-24987 |
STING activator diABZI-a1
STING agonist
|
STING activator diABZI-a1 is a potent, small molecule activator of STING, elicits IFNβ in human PBMCs with EC50 of 117 nM. |
