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Cat. No. Product Name Information
PC-60187

Cridanimod sodium

STING agonist

Cridanimod sodium (XBIO-101) is a potent type I interferon (IFN) inducer that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route.
PC-60186

Cridanimod

STING agonist

Cridanimod (10-CMA, XBIO-101, CMA) is a potent type I interferon (IFN) inducer that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route.
PC-45676

STING agonist G10

STING agonist

G10 (STING agonist G10) is a novel human-specific STING agonist; triggers IRF3/IFN-associated transcription in human fibroblasts.
PC-42754

DMXAA

STING agonist

DMXAA (ASA-404, Vadimezan) is a vascular disrupting agent (VDA) and competitive inhibitor of DT-diaphorase with Ki of 20 uM, also is a partial STING agonist, competes for human STING activation and STING dependent innate immune pathways.
PC-24987

STING activator diABZI-a1

STING agonist

STING activator diABZI-a1 is a potent, small molecule activator of STING, elicits IFNβ in human PBMCs with EC50 of 117 nM.
PC-24986

STING inhibitor diABZI-i

STING inhibitor

STING inhibitor diABZI-I (STING-IN-6) is a potent, small molecule inhibitor of STING, inhibits cGAMP-induced IFNβ in PBMCs with IC50 of 49 nM.
PC-24981

STING inhibitor 18

STING inhibitor

STING inhibitor 18 is a potent, orthosteric STING inhibitor / antagonist with IC50 of 68 nM in HAQ STING cGAMP displacement assay.
PC-24980

STING inhibitor THIQi

STING inhibitor

STING inhibitor THIQi is a potent, orthosteric STING inhibitor with IC50 of 84 nM in HAQ STING cGAMP displacement assays, inhibits cGAMP-induced IFNβ in PBMCs with IC50 of 29 nM.
PC-24871

Clonixeril

STING inhibitor

Clonixeril (CXL) is a highly potent, non-nucleotide hSTING modulator, has two modes of interaction with hSTING, shows weak agonist activity at micromolar concentrations, acts as a hSTING antagonist at <1 nM (EC50 < 1fM).
PC-24803

SR-301

STING agonist

SR-301 is a potent, non-nucleotide, oral small-molecule STING agonist with EC50 of 0.6 uM.
PC-24802

ZSA-215

STING agonist

ZSA-215 is a potent oral STING agonist with EC50 of 3.3 uM, enhances STING signaling through promoting the phosphorylation of STING and interferon regulatory factor 3 (IRF3) and secretion of IFN-β.
PC-24614

TAK-676

STING agonist

TAK-676 (Dazostinag disodium) is a potent, selective stimulator of interferon genes (STING) agonist with highly selective binding and activation of STING proteins from various species, with Kd values of 0.01 uM, 0.008 uM, 0.011 uM, and 0.027 uM for mouse, rat, cynomolgus monkey, and human STING orthologs, respectively.

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