| Cat. No. |
Product Name |
Information |
| PC-45676 |
STING agonist 1
STING agonist
|
G10 (STING Agonist 1) is a novel human-specific STING agonist; triggers IRF3/IFN-associated transcription in human fibroblasts. |
| PC-42754 |
DMXAA
STING agonist
|
DMXAA (ASA-404, Vadimezan) is a vascular disrupting agent (VDA) and competitive inhibitor of DT-diaphorase with Ki of 20 uM, also is a partial STING agonist, competes for human STING activation and STING dependent innate immune pathways. |
| PC-23577 |
Licochalcone D
STING inhibitor
|
Licochalcone D (Lico D) is a lycyrrhiza inflata-derived chalcone, potent and selective STING inhibitor, covalently modifies the Cys148 residue of STING and inhibits STING oligomerization. |
| PC-23402 |
Rhamnocitrin
cGAS/STING inhibitor
|
Rhamnocitrin is a flavonoid with anti-oxidant, anti-inflammatory and an-tiatherosclerosis activity, also shows antiviral activity against influenza virus H3N2 by inhibiting cGAS/STING pathway. |
| PC-23117 |
diABZI-4
STING agonist
|
diABZI-4 is a diamidobenzimidazole STING agonist, induces oligomerization of STING and activates STING and is highly effective in limiting SARS-CoV-2 replication. |
| PC-22732 |
BH400
PPARα agonist/STING inhibitor
|
BH400 is a potent, bifunctional PPARα/STING modulator, agonizes PPARα (EC50=1.2 μM) and inhibits STING (IC50=8.1 μM). |
| PC-38078 |
SN-011
STING inhibitor
|
SN-011 (SN011) is a potent, selective STING antagonist with IC50 of 76 nM (STING signaling inhibition). |
| PC-22730 |
SN-013
STING inhibitor
|
SN-013 is a potent, selective STING inhibitor, inhibits 2′3′-cGAMP-induced Ifnb gene expression with IC50 of 101.5 nM and 539.6 nM in MEF and HFF cells, respectively, targets the cyclic dinucleotide binding pocket. |
| PC-22635 |
IACS-8803 disodium
STING agonist
|
IACS-8803 disodium is a highly potent cyclic dinucleotide STING agonist, shows robust activation of the STING pathway. |
| PC-22439 |
STING degrader AK59
STING degrader
|
STING degrader AK59 (AK59-51TB) is a small molecule STING degrader leveraging HECT-domain E3 ligase HERC4, inhibits the cGAS/STING pathway via degradation of STING by proteasomal degradation. |
| PC-22431 |
BDW568
STING agonist
|
BDW568 is a non-nucleotide agonist of human STING (stimulator of interferon genes) and type-I interferon signaling activator. |
| PC-21157 |
LB244
STING inhibitor
|
LB244 (LB-244) is a highly potent, selective and irreversible STING antagonist, blocks STING oligomerization and inhibits STING signaling THP1 dual cells with IC50 of 0.8 uM. |
