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Cat. No. Product Name Information
PC-60187

Cridanimod sodium

STING agonist

Cridanimod sodium (XBIO-101) is a potent type I interferon (IFN) inducer that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route.
PC-60186

Cridanimod

STING agonist

Cridanimod (10-CMA, XBIO-101) is a potent type I interferon (IFN) inducer that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route.
PC-45676

STING agonist 1

STING agonist

G10 (STING Agonist 1) is a novel human-specific STING agonist; triggers IRF3/IFN-associated transcription in human fibroblasts.
PC-42754

DMXAA

STING agonist

DMXAA (ASA-404, Vadimezan) is a vascular disrupting agent (VDA) and competitive inhibitor of DT-diaphorase with Ki of 20 uM, also is a partial STING agonist, competes for human STING activation and STING dependent innate immune pathways.
PC-24094

Excavatolide B

STING inhibitor

Excavatolide B (ExcB) is a marine diterpenoid of covalent STING inhibitor, covalently engages STING at its membrane-proximal Cys91, inhibits STING palmitoylation and signaling, inhibits IFN-β levels in culture supernatants of THP1 macrophages with IC50 of 12.1 uM.
PC-24093

GHN105

STING inhibitor

GHN105 is a specific, orally bioavailable, covalent STING inhibitor, selectively targets the membrane-proximal Cys91 residue of STING, inhibits IFN-β levels in culture supernatants of THP1 macrophages with IC50 of 4.4 uM.
PC-24084

E7766 diammonium salt

STING agonist

E7766 diammonium salt is a macrocycle-bridged STING agonist with ITC Kd of 40 nM, exhibits broad pan-genotypic activity in all major human STING variants.
PC-23967

Astin C

STING inhibitor

Astin C is a specific, cyclopeptide inhibitor of cGAS-STING signaling, binds to STING C-terminal binding domain (CBD) with Kd of 2.37 uM (STING-CTD-H232), blocks the recruitment of IRF3 onto the STING signalosome and restricts STING activation and signaling.
PC-23966

STING inhibitor 42

STING inhibitor

STING inhibitor 42 is a potent, orally bioavailable STING inhibitor with IC50 of 34.2 nM and 7.1 nM for human and murine STING respectively.
PC-23719

DW18343

STING agonist

DW18343 is a specific, non-nucleotide stimulator of interferon genes (STING) agonist, binds to the LBD region of the STING protein, exhibits broad‐spectrum antitumor acitvity.
PC-23577

Licochalcone D

STING inhibitor

Licochalcone D (Lico D) is a lycyrrhiza inflata-derived chalcone, potent and selective STING inhibitor, covalently modifies the Cys148 residue of STING and inhibits STING oligomerization.
PC-23402

Rhamnocitrin

cGAS/STING inhibitor

Rhamnocitrin is a flavonoid with anti-oxidant, anti-inflammatory and an-tiatherosclerosis activity, also shows antiviral activity against influenza virus H3N2 by inhibiting cGAS/STING pathway.

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