| Cat. No. |
Product Name |
Information |
| PC-60186 |
Cridanimod
STING agonist
|
Cridanimod (10-CMA, XBIO-101) is a potent type I interferon (IFN) inducer that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route. |
| PC-45676 |
STING agonist 1
STING agonist
|
G10 (STING Agonist 1) is a novel human-specific STING agonist; triggers IRF3/IFN-associated transcription in human fibroblasts. |
| PC-42754 |
DMXAA
STING agonist
|
DMXAA (ASA-404, Vadimezan) is a vascular disrupting agent (VDA) and competitive inhibitor of DT-diaphorase with Ki of 20 uM, also is a partial STING agonist, competes for human STING activation and STING dependent innate immune pathways. |
| PC-23967 |
Astin C
STING inhibitor
|
Astin C is a specific, cyclopeptide inhibitor of cGAS-STING signaling, binds to STING C-terminal binding domain (CBD) with Kd of 2.37 uM (STING-CTD-H232), blocks the recruitment of IRF3 onto the STING signalosome and restricts STING activation and signaling. |
| PC-23966 |
STING inhibitor 42
STING inhibitor
|
STING inhibitor 42 is a potent, orally bioavailable STING inhibitor with IC50 of 34.2 nM and 7.1 nM for human and murine STING respectively. |
| PC-23719 |
DW18343
STING agonist
|
DW18343 is a specific, non-nucleotide stimulator of interferon genes (STING) agonist, binds to the LBD region of the STING protein, exhibits broad‐spectrum antitumor acitvity. |
| PC-23577 |
Licochalcone D
STING inhibitor
|
Licochalcone D (Lico D) is a lycyrrhiza inflata-derived chalcone, potent and selective STING inhibitor, covalently modifies the Cys148 residue of STING and inhibits STING oligomerization. |
| PC-23402 |
Rhamnocitrin
cGAS/STING inhibitor
|
Rhamnocitrin is a flavonoid with anti-oxidant, anti-inflammatory and an-tiatherosclerosis activity, also shows antiviral activity against influenza virus H3N2 by inhibiting cGAS/STING pathway. |
| PC-23117 |
diABZI-4
STING agonist
|
diABZI-4 is a diamidobenzimidazole STING agonist, induces oligomerization of STING and activates STING and is highly effective in limiting SARS-CoV-2 replication. |
| PC-22732 |
BH400
PPARα agonist/STING inhibitor
|
BH400 is a potent, bifunctional PPARα/STING modulator, agonizes PPARα (EC50=1.2 μM) and inhibits STING (IC50=8.1 μM). |
| PC-38078 |
SN-011
STING inhibitor
|
SN-011 (SN011) is a potent, selective STING antagonist with IC50 of 76 nM (STING signaling inhibition). |
| PC-22730 |
SN-013
STING inhibitor
|
SN-013 is a potent, selective STING inhibitor, inhibits 2′3′-cGAMP-induced Ifnb gene expression with IC50 of 101.5 nM and 539.6 nM in MEF and HFF cells, respectively, targets the cyclic dinucleotide binding pocket. |
