| Cat. No. |
Product Name |
Information |
| PC-35312 |
STING inhibitor H-151
STING inhibitor
|
STING inhibitor H-151 (H151) is a highly potent, selective, covalent small-molecule antagonist of STING that has noteworthy inhibitory activity both in human cells and in vivo. |
| PC-35311 |
STING inhibitor C-176
STING inhibitor
|
STING inhibitor C-176 (C176) is a covalent, in vivo-active, small-molecule inhibitor of STING, attenuates STING-associated autoinflammatory disease in mice. |
| PC-35310 |
STING inhibitor C-178
STING inhibitor
|
STING inhibitor C-178 is a covalent, small-molecule inhibitor of STING, blocks palmitoylation (PMA)-induced clustering of STING. |
| PC-63270 |
ChX710
ISRE inducer, STING agonist
|
ChX710 (ChX0306710) is a small molecule Interferon-Stimulated Response Elements (ISRE) inducer that primes the type I interferon response to cytosolic DNA, which is dependent on the adaptor MAVS and IRF1, but not the IRF3. |
| PC-43284 |
ADU-S100 ammonium salt
STING agonist
|
ML RR-S2 CDA ammonium salt is a synthetic cyclic dinucleotide derivative that functions as a highly potent agonist of STING, enhances binding affinity to STING and activates all known human STING alleles. |
| PC-43283 |
ADU-S100
STING agonist
|
ADU-S100 (MIW815, ML RR-S2 CDA) is a synthetic cyclic dinucleotide derivative that functions as a highly potent agonist of STING, enhances binding affinity to STING and activates all known human STING alleles. |
| PC-62663 |
cGAMP
STING agonist
|
cGAMP is a potent STING activator that binds to hSTING R232 and hSTING A230/R232 with Kd of 0.11 uM and 0.16 uM, respectively. |
| PC-62660 |
2 3-cGAMP
STING agonist
|
2′3′-cGAMP is a potent STING activator that binds to STING with Kd of 1.61 uM. |
| PC-62639 |
ADU-S100 disodium salt
STING agonist
|
ADU-S100 (MIW815, ML RR-S2 CDA) disodium salt is a synthetic cyclic dinucleotide derivative that functions as a highly potent agonist of STING, enhances binding affinity to STING and activates all known human STING alleles. |
| PC-61228 |
STING agonist C11
STING agonist
|
STING agonist C11 is a novel cell-permeable STING agonist that activates IFN-dependent signaling processes and induces IFN secretion from human cells. |
| PC-60187 |
Cridanimod sodium
STING agonist
|
Cridanimod sodium (XBIO-101) is a potent type I interferon (IFN) inducer that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route. |
| PC-60186 |
Cridanimod
STING agonist
|
Cridanimod (10-CMA, XBIO-101) is a potent type I interferon (IFN) inducer that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route. |
