| Cat. No. |
Product Name |
Information |
| PC-23121 |
DC-TEADin02
TEAD inhibitor
|
DC-TEADin02 is a potent, selective, covalent TEAD autopalmitoylation inhibitor with IC50 of 197 nM, shows minimal effect on TEAD-YAP interaction. |
| PC-23113 |
YAP-TEAD inhibitor BY03
YAP-TEAD inhibitor
|
BY03 is a small molecule inhibitor of YAP-TEAD interaction with IC50 of 1.5 uM in TEAD-dependent luciferase assay in overexpressing the TEAD luciferase plasmid in HEK293T. |
| PC-22052 |
BAY-6092
YAP1/TAZ inhibitor
|
BAY-6092 (BAY6092) is a potent, selective YAP1/TAZ pathway inhibitor with IC50 of 1.6 nM in TEAD-luciferase assays, directly tareget PGGT1B, a subunit of the geranylgeranyltransferase-I (GGTase-I) complex. |
| PC-22051 |
BAY-856
YAP1/TAZ inhibitor
|
BAY-856 (BAY856) is a potent, selective YAP1/TAZ pathway inhibitor with IC50 of 49 nM in TEAD-luciferase assays, directly tareget PGGT1B, a subunit of the geranylgeranyltransferase-I (GGTase-I) complex. |
| PC-22050 |
BAY-593
YAP1/TAZ inhibitor
|
BAY-593 (BAY593) is a potent, selective, in vivo-active YAP1/TAZ pathway inhibitor with IC50 of 9.4 nM in TEAD-luciferase assays, directly tareget PGGT1B, a subunit of the geranylgeranyltransferase-I (GGTase-I) complex. |
| PC-21253 |
AF-2112
TEAD inhibitor
|
AF-2112 is a small molecule inhibitor of TEAD, reduces the expression of CTGF, Cyr61, Axl and NF2, inhibits migration of human MDA-MB-231 breast cancer cells. |
| PC-21252 |
TEAD inhibitor LM41
TEAD inhibitor
|
TEAD inhibitor LM41 is a small molecule inhibitor of TEAD, reduces the expression of CTGF, Cyr61, Axl and NF2, inhibits migration of human MDA-MB-231 breast cancer cells. |
| PC-49185 |
TAT-PDHPS1
YAP inhibitor
|
TAT-PDHPS1 is an endogenous stable peptide that inhibits the proliferation of ovarian cancer cells in vitro, regulates ovarian cancer development through targeting YAP1 signaling, binds to and interacts with protein phosphatase 2 phosphatase activator (PTPA). |
| PC-49184 |
PDHPS1
YAP inhibitor
|
PDHPS1 is an endogenous stable peptide which is derived from the C-terminal (2090-2110) of NUMA1, inhibits the proliferation of ovarian cancer cells in vitro, regulates ovarian cancer development through targeting YAP1 signaling, binds to and interacts with protein phosphatase 2 phosphatase activator (PTPA). |
