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Cat. No. Product Name Information
PC-22893

VU6036864

M5 mAChR antagonist

VU6036864 is a highly potent, selective antagonist of muscarinic acetylcholine receptor mAChR subtype 5 (M5) with IC50 of 25 nM (hM5), >500 fold selectivity against M1-4 receptors.
PC-22795

PIPE-307

M1 mAChR antagonist

PIPE-307 is a potent, selective, orally bioavailable, brain-penetrant antagonist of M1 muscarinic acetylcholine receptor (M1R, M1 mAChR) with Ki of 4.6 nM in membranes overexpressing human M1R.
PC-22509

CHF-6550

MABA

CHF-6550 is a potent, dual acting muscarinic M3 antagonist and β2 agonist (MABA) with pKi values of 9.3 and 10.6 for M3 and β2 receptor, respectively.
PC-21369

VU 0365114

M5 mAChR PAM

VU 0365114 is a selective type-5 muscarinic acetylcholine receptor (mAChR, M5) positive allosteric modulator (EC50=2.7 uM) and tubulin inhibitor by destabilizing microtubules, shows no activity against M1, M2, M3 and M4 receptors.
PC-43517

Xanomeline oxalate

Xanomeline oxalate (LY246708, NNC 110232) is a potent, specific M1 muscarinic agonist with functional selectivity for M1 receptor (binding IC50 of 6 pM in the rabbit vas deferens).
PC-43389

Biperiden hydrochloride

Biperiden Hcl (NSC 170950, NSC 84989) is a centrally-acting antiparkinsonian agent that functions as a selective central M1 cholinoreceptors blocker..
PC-61893

Fesoterodine fumarate

Fesoterodine (PF-00695838) is a competitive muscarinic receptor antagonist with muscle relaxant and urinary antispasmodic properties.
PC-61892

Fesoterodine maleate

Fesoterodine (PF-00695838) is a competitive muscarinic receptor antagonist with muscle relaxant and urinary antispasmodic properties.
PC-61761

Glycopyrronium bromide

Glycopyrronium bromide (CHF 5259) is a peripherally-acting quaternary ammonium antimuscarinic agent with little or no central nervous system activity.
PC-42262

Pirmenol hydrochloride

An orally effective, long-acting antiarrhythmic agent that interacts with cardiac muscarinic receptors..
PC-45938

Cevimeline

A potent M1-selective muscarinic agonist.
PC-45283

Glycopyrrolate

A muscarinic anticholinergic that blocks muscarinic receptors, thus inhibiting cholinergic transmission..

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